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ARS Home » Pacific West Area » Albany, California » Western Regional Research Center » Produce Safety and Microbiology Research » Research » Publications at this Location » Publication #319526

Research Project: Immunodiagnostics to Detect Prions and Other Important Animal Pathogens

Location: Produce Safety and Microbiology Research

Title: Monoclonal antibody technologies and rapid detection assays

Author
item Hnasko, Robert
item Stanker, Larry
item McGarvey, Jeffery - Jeff

Submitted to: Meeting Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 9/24/2015
Publication Date: 10/1/2015
Citation: Hnasko, R.M., Stanker, L.H., Mcgarvey, J.A. 2015. Monoclonal antibody technologies and rapid detection assays.September 23-25, 2015 Carlsbad, CA: p. 1-44.

Interpretive Summary: Research and development methods are described for the generation of monoclonal antibodies and their use in mobile immunoassay platforms to improve animal health and food safety.

Technical Abstract: Novel methodologies and screening strategies will be outlined on the use of hybridoma technology for the selection of antigen specific monoclonal antibodies. The development of immunoassays used for diagnostic detection of prions and bacterial toxins will be discussed and examples provided demonstrating rapid detection methods that include lateral flow test strips and microfluidic devices.