Location: Produce Safety and Microbiology ResearchTitle: The complete genome sequence and annotation of a Campylobacter jejuni strain, MTVDSCj20, isolated from a naturally colonized farm-raised chicken Author
|Taveirne, Michael - University Of Michigan Medical School|
|Dunham, Drew - University Of Michigan Medical School|
|Miller, William - Bill|
|Dirita, Victor - University Of Michigan Medical School|
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/4/2014
Publication Date: 8/21/2014
Citation: Taveirne, M.E., Dunham, D.T., Miller, W.G., Parker, C., Huynh, S., Dirita, V.J. 2014. The complete genome sequence and annotation of a Campylobacter jejuni strain, MTVDSCj20, isolated from a naturally colonized farm-raised chicken. Genome Announcements. 2(4):e00852-14. doi: 10.1128/genomeA.00852-14.
Interpretive Summary: Campylobacter jejuni is a leading cause of bacterially-derived human foodborne illness worldwide. Human Campylobacter derived gastroenteritis, campylobacteriosis, is predominantly caused by two species of campylobacters, C. jejuni and C. coli. Campylobacter infections are usually due to consumption of contaminated poultry products, mainly chicken. Colonization of broiler chickens with campylobacters usually occurs after 2-weeks of age and can persist until slaughter, with high levels of campylobacters isolated form the ceca. In an effort to better understand colonization mechanisms employed by campylobacters during a natural infection, a strain was isolated from a farm-raised chicken; the chromosome of this bacterial strain was sequenced to determine its gene content and similarity to other campylobacters.
Technical Abstract: Campylobacter jejuni is a major cause of human foodborne illness worldwide with contaminated poultry products serving as a main source of human infection. C. jejuni strain MTVDSCj20 was isolated from the cecal contents of a farm-raised chicken naturally colonized with Campylobacter. The complete, annotated genome sequence is 1.65 Mbp long and encodes 1,714 open reading frames.