Dr. Pearce acts as a Research Animal Physiologist within the Agroecosystems Management Research Unit at NLAE. The Research is conducted under the ARS National Research Program 101-Food Animal Production. The goals of Dr. Pearce’s personal research are to determine the impact of nutrition programs (e.g., phytochemicals), external environmental stressors (e.g., heat stress), and internal physiological stressors (e.g., pathogens) on basic and applied mechanisms in the gastrointestinal tract necessary to maintain or improve animal productivity, reduce oxidative stress, and maintain the structural integrity of the gastrointestinal tract.

• Publications

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  • Dietary isoacids effects on growth, nitrogen, and energy digestibility, and colonic VFA and microbial ecology in finishing pigs-(Peer Reviewed Journal)
    
    
  • Effects of aronia melanocarpa juice-powder on hindgut function and performance in post-weaned pigs -(Peer Reviewed Journal)
    Pearce, S.C., Anderson, C.L., Kerr, B.J. 2024. Effects of aronia melanocarpa juice-powder on hindgut function and performance in post-weaned pigs. Journal of Functional Foods. 116. Article 106196. https://doi.org/10.1016/j.jff.2024.106196.
    
  • Effects of dietary protein level on intestinal function and inflammation in nursery pigs -(Peer Reviewed Journal)
    Pearce, S.C., Nisley, M.J., Kerr, B.J., Sparks, C., Gabler, N.K. 2024. Effects of dietary protein level on intestinal function and inflammation in nursery pigs. Journal of Animal Science. 102. Article skae077. https://doi.org/10.1093/jas/skae077.
    
  • Hypoxia exacerbates heat stress effects on the porcine intestinal epithelium in vitro -(Peer Reviewed Journal)
    Pearce, S.C., Gabler, N.K. 2023. Hypoxia exacerbates heat stress effects on the porcine intestinal epithelium in vitro. Frontiers in Animal Science . 4. https://doi.org/10.3389/fanim.2023.1204152.
    
  • Soluble corn fiber, resistant corn starch, and protected butyrate effects on performance, gastrointestinal volatile fatty acids, and apparent total-tract digestibility of calcium and phosphorus in nursery pigs -(Peer Reviewed Journal)
    Kerr, B.J., Pearce, S.C., Ramirez, S.M., Schweer, W.P., Gabler, N.K. 2023. Soluble corn fiber, resistant corn starch, and protected butyrate effects on performance, gastrointestinal volatile fatty acids, and apparent total-tract digestibility of calcium and phosphorus in nursery pigs. Journal of Animal Science. 101. Article skad022. https://doi.org/10.1093/jas/skad022.
    
  • Effects of short-chain fatty acids on intestinal function in an enteroid model of hypoxia -(Peer Reviewed Journal)
    Pearce, S.C., Karl, J.P., Weber, G.J. 2022. Effects of short-chain fatty acids on intestinal function in an enteroid model of hypoxia. Frontiers in Physiology. 13. https://doi.org/10.3389/fphys.2022.1056233.
    
  • Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity -(Peer Reviewed Journal)
    Kerr, B.J., Trachsel, J.M., Bearson, B.L., Loving, C.L., Bearson, S.M., Byrne, K.A., Pearce, S.C., Ramirez, S.M., Gabler, N.K., Schweer, W.P., Helm, E.T., De Mille, C.M. 2022. Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity. Journal of Animal Science. 100(11). Article skac282. https://doi.org/10.1093/jas/skac282.
    
  • Human iPSC colon organoid function is improved by exposure to fecal fermentates -(Peer Reviewed Journal)
    Pearce, S.C., Weber, G.J., Doherty, L.A., Soares, J.W. 2022. Human iPSC colon organoid function is improved by exposure to fecal fermentates. Journal of Federation of American Societies for Experimental Biology. 4(7):468-484. https://doi.org/10.1096/fba.2021-00166.
    
  • Effects of dietary protein level on intestinal function and inflammation in growing pigs-(Abstract Only)
    Pearce, S.C., Nisley, M., Gabler, N.K., Sparks, C. 2022. Effects of dietary protein level on intestinal function and inflammation in growing pigs [abstract]. International Symposium on Digestive Physiology in Pigs.
    
  • Expression of SARS-CoV-2 entry factors, electrolyte and mineral transporters in different mouse intestinal epithelial cell types -(Peer Reviewed Journal)
    Pearce, S.C., Suntornsaratoon, P., Kishida, K., Al-Jawadi, A., Guadria, J., Nadler, I., Flores, J., Shiarella, R., Auvinen, M., Gao, N., Ferraris, R.P. 2021. Expression of SARS-CoV-2 entry factors, electrolyte and mineral transporters in different mouse intestinal epithelial cell types. Physiological Reports. 9(21). Article e15061. https://doi.org/10.14814/phy2.15061.
    

• Projects

  Physiological, Microbiological, and Nutritional Mechanisms to Maintain Animal Productivity in the Absence of Antibiotics In-House Appropriated (D)   Accession Number:442600

  Utilizing the Iowa State University Animal Care and Use Committee Non-Funded Cooperative Agreement (N)   Accession Number:440918

• ARS News Articles

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