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United States Department of Agriculture

Agricultural Research Service

Related Topics

Reuven Rasooly
Foodborne Toxin Detection and Prevention Research
Chemistry

Phone: (510) 559-6478
Fax: (510) 559-6429

USDA, ARS, PWA, WRRC-FTDP
800 BUCHANAN ST
ALBANY , CA 94710

Projects
Advance the Development of Technologies for Detecting and Determining the Stability and Bioavailability of Toxins that Impact Food Safety and Food Defense
Appropriated (D)
  Accession Number: 430056

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E -
Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E. Toxins. 8(5):150. doi: 10.3390/toxins8050150.
Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1 -
Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1. Journal of Agricultural and Food Chemistry. 80:405-410.
A new immunoassay for detecting all subtypes of Shiga toxins produced by Shiga toxin-producing E. coli in ground beef -
He, X., Kong, Q., Patfield, S.A., Skinner, C.B., Rasooly, R. 2016. A new immunoassay for detecting all subtypes of Shiga toxins produced by Shiga toxin-producing E. coli in ground beef. PLoS One. 11(1):e0148092.
Plant compounds enhance assay sensitivity for detection of active bacillus cereus toxin Reprint Icon -
Rasooly, R., Hernlem, B.J., He, X., Friedman, M. 2015. Plant compounds enhance assay sensitivity for detection of active bacillus cereus toxin. Toxins. 7(3):835-845. doi: 10.3390/toxins7030835.
Sensitive detection of active Shiga toxin using low cost CCD based optical detector Reprint Icon -
Rasooly, R., Balsam, J., Hernlem, B.J., Rasooly, A.J. 2015. Sensitive detection of active Shiga toxin using low cost CCD based optical detector. Biosensors and Bioelectronics. 68:705-711.
Quantitative analysis of Staphylococcus enterotoxin A by differential expression of IFN-gamma in splenocyte and CD4+ T-cells Reprint Icon -
Rasooly, R., Hernlem, B.J. 2014. Quantitative analysis of Staphylococcus enterotoxin A by differential expression of IFN-gamma in splenocyte and CD4+ T-cells. Sensors. 14:8869-8876 DOI:10.3390/s140508869.
Electron-beam is effective in reducing Escherichia coli on blueberries and extending the shelf life of the fruits Reprint Icon -
Kong, Q., Wu, A., Qi, W., Qi, R., Carter, J.M., Rasooly, R., He, X. 2014. Electron-beam is effective in reducing Escherichia coli on blueberries and extending the shelf life of the fruits. Postharvest Biology and Technology. 95(2014):28-35.
Microwave heating inactivates Shiga Toxin (Stx2) in reconstituted fat-free Milk and adversely affects the nutritional value of cell culture medium Reprint Icon -
Rasooly, R., Hernlem, B.J., He, X., Friedman, M. 2014. Microwave heating inactivates Shiga Toxin (Stx2) in reconstituted fat-free Milk and adversely affects the nutritional value of cell culture medium. Journal of Agricultural and Food Chemistry. 62:3301-3305 DOI.org/10.1021/jf500278a.
A polyclonal antibody based immunoassay detects seven subtypes of Shiga toxin 2 produced by escherichia coli in human and environmental samples -
He, X., Patfield, S.A., Hnasko, R.M., Rasooly, R., Mandrell, R.E. 2013. A polyclonal antibody based immunoassay detects seven subtypes of Shiga toxin 2 produced by escherichia coli in human and environmental samples. PLoS One. 8(10):e76368.
Non-linear relationships between aflatoxin B1 levels and the biological response of monkey kidney vero cells Reprint Icon -
Rasooly, R., Hernlem, B.J., He, X. 2013. Non-linear relationships between aflatoxin B1 levels and the biological response of monkey kidney vero cells. Toxins. 5:1447-1461. doi:10.3390/toxins5081447.
Low levels of aflatoxin B1, ricin and milk enhance recombinant protein production in mammalian cells Reprint Icon -
Rasooly, R., Hernlem, B.J., Friedman, M. 2013. Low levels of aflatoxin B1, ricin and milk enhance recombinant protein production in mammalian cells. PLoS One. 8(8):e71682. doi:10.1371/journal.pone.0071682.
Thousand-fold fluorescent signal amplification for mHealth diagnostics Reprint Icon -
Balsam, J., Rasooly, R., Bruck, H.A., Rasooly, A. 2013. Thousand-fold fluorescent signal amplification for mHealth diagnostics. Biosensors and Bioelectronics. 51:1-7.
Review of the inhibition of biological activities of selected food-related toxins by natural compounds -
Friedman, M., Rasooly, R. 2013. Review of the inhibition of biological activities of selected food-related toxins by natural compounds. Toxins. 5:743-775. doi: 10.3390/toxins50x100x.
Purification and characterization of Shiga toxin 2f, an immunologically unrelated subtype of Shiga toxin 2 Reprint Icon -
Skinner, C.B., Patfield, S.A., Rasooly, R., Carter, J.M., He, X. 2013. Purification and characterization of Shiga toxin 2f, an immunologically unrelated subtype of Shiga toxin 2. PLoS One. 8(3):e59760.
Milk inhibits the biological activity of ricin -
Rasooly, R., He, X., Friedman, M. 2012. Milk inhibits the biological activity of ricin. Journal of Biological Chemistry. 287(33):27924-27929. doi:10.1074/jbc.M112.362988.
TNF as biomarker for rapid quantification of active Staphylococcus enterotoxin A in food -
Rasooly, R., Hernlem, B.J. 2012. TNF as biomarker for rapid quantification of active Staphylococcus enterotoxin A in food. Sensors. 12:5978-5985. doi:10.3390/s120505978.
Techniques for rapid detection and quantification of active foodborne Staphylococcus Enterotoxin(Abstract) -
Hernlem, B.J., Rasooly, R. 2012. Techniques for rapid detection and quantification of active foodborne Staphylococcus Enterotoxin(Abstract). Meeting Abstract. Poster no. B266.
Sensitive bioassay for detection of biologically active ricin in food -
Rasooly, R., He, X. 2012. Sensitive bioassay for detection of biologically active ricin in food. Journal of Food Protection. 75(5):951-954.
CD154 as a potential early molecular biomarker for rapid quantification analysis of active Staphylococcus enterotoxin A -
Rasooly, R., Hernlem, B.J. 2011. CD154 as a potential early molecular biomarker for rapid quantification analysis of active Staphylococcus enterotoxin A. FEMS Immunology and Medical Microbiology. 64(2):169-174.
Evaluation and comparison of three enzyme-linked immunosorbent assay formats for the detection of ricin in milk and serum -
He, X., Mcmahon, S.A., Rasooly, R. 2012. Evaluation and comparison of three enzyme-linked immunosorbent assay formats for the detection of ricin in milk and serum. Biocatalysis and Agricultural Biotechnology. 1(2):105-109. doi:10.1016/j.bcab.2011.08.016.
Food compounds inhibit Staphylococcus aureus bacteria and the toxicity of Staphylococcus Enterotoxin A (SEA) associated with atopic dermatitis -
Rasooly, R., Friedman, M. 2012. Food compounds inhibit Staphylococcus aureus bacteria and the toxicity of Staphylococcus Enterotoxin A (SEA) associated with atopic dermatitis. In: Esparza-Gordillo, J., editor. Atopic Dermatitis-Disease Etiology and Clinical Management. Croatia: Intech Europe. p. 387-404
The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA) -
Friedman, M., Rasooly, R., Do, P.M., Henika, P.R. 2011. The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA). Journal of Food Science. 76:M558-M558. doi:10.1111/j.1750-3841.2001.02365.x.
Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells -
Rasooly, R., Do, P.M., Hernlem, B.J. 2011. Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells. Open Journal of Immunology. 1(1):8-14. doi:10.4236/oji.2011.11002.
Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization -
Rasooly, R., Do, P.M. 2010. Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization. Journal of Agricultural and Food Chemistry. 58:12557-12561.
Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice -
Rasooly, R., Do, P.M., Griffey, S.M., Vilches-Moure, J.G., Friedman, M. 2010. Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice. Journal of Agricultural and Food Chemistry. (58):9821-9286
Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols -
Rasooly, R., Do, P.M., Friedman, M. 2010. Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols. Journal of Agricultural and Food Chemistry. 58:5421-5426.
Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization -
Rasooly, R., Do, P.M., Levin, C.E., Friedman, M. 2010. Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization. Applied and Environmental Microbiology. Vol. 75(5):M296-M301.
Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization Reprint Icon -
Rasooly, R., Do, P.M. 2009. Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization. International Journal of Food Microbiology. 136(2010):290-294
Detection of Protein Toxins -
Brandon, D.L., Cheng, L.W., He, X., Rasooly, R., Scotcher, M.C., Stanker, L.H., Carter, J.M. 2009. Detection of Protein Toxins. Meeting Abstract. Poster No. 8.
In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food -
Rasooly, R., Do, P.M. 2009. In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food. FEMS Immunology and Medical Microbiology 56(2009): 172-178.
Immunochemical technologies for replacement of rodent bioassays in sensitive detection of toxins in foods -
Carter, J.M., Cheng, L.W., He, X., Rasooly, R., Brandon, D.L., Stanker, L.H. 2010. Immunochemical technologies for replacement of rodent bioassays in sensitive detection of toxins in foods. Proceedings from Biodetection Technologies 6th Edition. 5:75-95.
Effect of food matrices on the biological activity of ricin -
He, X., Lu, S.S., Cheng, L.W., Rasooly, R., Carter, J.M. 2008. Effect of food matrices on the biological activity of ricin. Journal of Food Protection 71(10):2053-2058.
In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food -
Rasooly, R., Do, P.M. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. Applied and Environmental Microbiology. 74(14):4309-4313
Bactericidal activity of the food color additive Phloxine B against Staphylococcus aureus and other food borne microbial pathogens -
Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay -
Rasooly, R., Stanker, L.H., Carter, J.M., Do, P.M., Cheng, L.W., He, X., Brandon, D.L. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. International Journal of Food Microbiiology. 126 (2008):135-139
Docosahexaenoic Acid (DHA) But Not Eicosapentaenoic Acid (EPA) Reverses Trans-10, Cis-12 Conjugated Linoleic Acid Induced Insulin Resistance in Mice1 -
Vemuri, M., Kelley, D.S., Mackey, B.E., Rasooly, R., Bartolini, G.L. Docosahexaenoic Acid (DHA) But Not Eicosapentaenoic Acid (EPA) Reverses Trans-10, Cis-12 Conjugated Linoleic Acid Induced Insulin Resistance in Mice. Metabolic Syndrome and Related Disorders, 2007 Vol.5, No.4:315-322.
Phloxine B, aversatile bacterial stain -
Rasooly, R. 2007. Phloxine B, aversatile bacterial stain. International Journal of Food Microbiology.157: 29-34.
DIETARY T10, C-12-CONJUGATED LINOLEIC ACID REDUCES THE EXPRESSION OF FATTY ACID OXIDATION AND DRUG DETOXIFICATION ENZYMES IN MOUSE LIVER -
Rasooly, R., Kelley, D.S., Greg, J., Mackey, B.E. Dietary t10, c-12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Journal of Nutrition. 97:58-66, 2007.
CONSUMPTION OF BING SWEET CHERRIES LOWERS CIRCULATING CONCENTRATIONS OF INFLAMMATION MARKERS IN HEALTHY MEN AND WOMEN -
Kelley, D.S., Rasooly, R., Jacob, R.A., Kader, A.A., Mackey, B.E. 2006. CONSUMPTION OF BING SWEET CHERRIES LOWERS CIRCULATING CONCENTRATIONS OF INFLAMMATION MARKERS IN HEALTHY MEN AND WOMEN. Journal of Nutrition. 136:981-986, 2006.
RETINOID X RECEPTOR AGONISTS INCREASE BCL2A1 EXPRESSION AND DECREASE APOPTOSIS OF NAÏVE T LYMPHOCYTES -
Rasooly, R., Schuster, G.U., Gregg, J.P., Xiao, J.H., Chandraratna, R., Stephensen, C.B. 2005. RETINOID X RECEPTOR AGONISTS INCREASE BCL2A1 EXPRESSION AND DECREASE APOPTOSIS OF NAÏVE T LYMPHOCYTES. Journal of Immunology. 175:7916-7929.
ARS News Articles
Last Modified: 5/2/2016
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