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ARS Home » Southeast Area » Stuttgart, Arkansas » Harry K. Dupree Stuttgart National Aquaculture Research Cntr » Research » Publications at this Location » Publication #97726
Title: EFFECT OF WATERBORNE POTASSIUM PERMANGANATE ON MANGANESE CONTENT IN LIVER AND AXIAL MUSCLE OF CHANNEL CATFISH

Author
item Griffin, Billy
item Franks, Jan
item Hobbs, Melissa
item KADLUBAR, FRED - NCTR
item BRAND, C - NCTR

Submitted to: Journal of Aquatic Animal Health
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 7/21/1999
Publication Date: N/A
Citation: N/A

Interpretive Summary: To meet the needs of FDA in evaluating the human food safety of potassium permanganate as a disease treatment for fish, channel catfish were exposed to different concentrations of waterborne potassium permanganate for 12 weeks during which time liver and muscle samples samples were collected and analyzed for manganese content. The study was conducted under the auspices of the Good Laboratory Practices Act. The study showed that exposure to near lethal concentrations of potassium permanganate for 12 weeks did not alter liver or muscle concentrations of manganese. The conclusion from the study is that use of potassium permangaanate as a disease therapeutant in channal catfish poses no hazard to human consumers.

Technical Abstract: To meet the needs of FDA in evaluating the human food safety of potassium permanganate as a disease treatment for fish, channel catfish were exposed to different concentrations of waterborne potassium permanganate for 12 weeks during which time liver and muscle samples samples were collected and analyzed for manganese content. The study was conducted under the auspices of the Good Laboratory Practices Act. The study showed that exposure to incipient lethal concentrations of potassium permanganate for 12 weeks did not alter liver or muscle concentrations of manganese. The conclusion from the study is that use of potassium permangaanate as a disease therapeutant in channal catfish poses no hazard to human consumers.