Location: Cereal Crops ResearchTitle: Characterization of effectors and their targets in necrotrophic pathogens reveals trends and variation in host manipulation
Submitted to: Annual Review of Phytopathology
Publication Type: Review Article
Publication Acceptance Date: 3/17/2021
Publication Date: 4/28/2021
Citation: Friesen, T.L., Faris, J.D. 2021. Characterization of effectors and their targets in necrotrophic pathogens reveals trends and variation in host manipulation. Annual Review of Phytopathology. 59:4.1-4.22. https://doi.org/10.1146/annurev-phyto-120320-012807.
Technical Abstract: Great strides have been made in defining the details of the plant defense response involving biotrophic fungal and bacterial pathogens. The groundwork for the current model was laid by HH Flor and others who defined the gene for gene hypothesis that involved what we now know as effector triggered immunity (ETI). PAMP triggered immunity (PTI) has also been shown to be a highly effective response to most pathogens due to the recognition of common pathogen molecules by pattern recognition receptors (PRRs). In this review, we will use the three pathogens that make up the foliar disease complex of wheat, Zymoseptoria tritici, Pyrenophora tritici-repentis, and Parastagonospora nodorum, to review the means by which necrotrophic pathogens are circumventing or outright hijacking the ETI and PTI pathways to cause disease.