Location: Cereal Crops ResearchTitle: Plant genes hijacked by necrotrophic fungal pathogens
Submitted to: Current Opinion in Plant Biology
Publication Type: Review Article
Publication Acceptance Date: 4/7/2020
Publication Date: 5/31/2020
Citation: Faris, J.D., Friesen, T.L. 2020. Plant genes hijacked by necrotrophic fungal pathogens. Current Opinion in Plant Biology. 56:74-80. https://doi.org/10.1016/j.pbi.2020.04.003.
Interpretive Summary: .
Technical Abstract: Plant fungal pathogens can be classified according to their lifestyles. Biotrophs feed on living tissue and constitute an economically significant group of pathogens historically. Necrotrophs, which feed on dead tissue, have become economically significant over recent decades, especially those of the Dothideomycetes, which produce necrotrophic effectors (NEs) to modulate the host response. These pathogens interact with their hosts in an inverse gene-for-gene manner, where NEs are recognized by specific dominant genes in the host leading to host-induced programmed cell death allowing the pathogen to cause disease. Whereas the NE genes tend to be unique, several of the plant ‘susceptibility’ genes belong to the nucleotide-binding leucine-rich repeat class of disease ‘resistance’ genes, and one is a wall-associated kinase. These susceptible interactions exhibit hallmarks of defense responses to biotrophic pathogens. Therefore, there is now accumulating evidence that necrotrophic specialists hijack the resistance mechanisms that are effective against biotrophic pathogens.