|BERTRAN, KATERI - Consultant|
|TORCHETTI, MIA - Animal And Plant Health Inspection Service (APHIS)|
Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 7/14/2017
Publication Date: N/A
Technical Abstract: In early March of 2017 an outbreak of highly pathogenic avian influenza H7N9 was reported from a broiler-breeder flock Tennessee. A second HPAI case was detected 2 weeks later. Subsequent active and passive surveillance identified several LPAI cases in Alabama, Georgia, Kentucky, and TN that was genetically related to the HPAI cases. Epidemiologically it isn’t clear about the connection between the different farms. Sequence analysis of the HPAI cases showed it was most closely related to wild bird low pathogenic viruses of North American origin, and was unrelated to the Chinese H7N9 viruses. The HPAI virus had a 9 amino acid insert at the hemagglutinin cleavage site, apparently from host rRNA by non-homologous recombination. Pathogenesis studies are ongoing.