Skip to main content
ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Meat Safety & Quality Research » Research » Publications at this Location » Publication #323722

Research Project: Exploring Genomic Differences and Ecological Reservoirs To Control Foodborne Pathogens

Location: Meat Safety & Quality Research

Title: Complete closed genome sequences of Salmonella enterica subsp. enterica serotypes Anatum, Montevideo, Typhimurium and Newport, isolated from beef, cattle, and humans

Author
item Harhay, Dayna
item Bono, James - Jim
item Smith, Timothy - Tim
item Fields, Patricia - Centers For Disease Control And Prevention (CDCP) - United States
item Dinsmore, Blake - Centers For Disease Control And Prevention (CDCP) - United States
item Santovenia, Monica - Centers For Disease Control And Prevention (CDCP) - United States
item Kelley, Christy
item Wang, Rong
item Harhay, Gregory

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/9/2015
Publication Date: 2/4/2016
Publication URL: http://handle.nal.usda.gov/10113/61841
Citation: Harhay, D.M., Bono, J.L., Smith, T.P., Fields, P.I., Dinsmore, B.A., Santovenia, M., Kelley, C.M., Wang, R., Harhay, G.P. 2016. Complete closed genome sequences of Salmonella enterica subsp. enterica serotypes Anatum, Montevideo, Typhimurium and Newport, isolated from beef, cattle, and humans. Genome Announcements. 4(1):e01683-15. doi:10.1128/genomeA.01683-15.

Interpretive Summary: Salmonella enterica are a diverse group of bacteria, generally found everywhere in nature, and capable of surviving in the environment as well as many different hosts with varying degrees of impact, from harmless colonization to invasive infection. Recent outbreaks of disease caused by multi-drug resistant Salmonella have led to increased scrutiny on the presence of these pathogens in meat, and there has been mounting pressure from various groups for greater regulation of certain Salmonella in ground beef and other meat products. Given the potential for future regulation, beef producers will likely need tools for rapid detection of particular Salmonella strains when present as contaminants of meat. In order to develop tests to detect Salmonella contamination, genomic sequence data of disease-causing and harmless Salmonella is needed. This project produced complete genome sequences of eight Salmonella strains, two each of four different serotypes isolated from cattle, beef, or human samples. The differences identified by these sequences of pathogenic and harmless strains of Salmonella will lead to accurate detection tests.

Technical Abstract: Salmonella enterica are a versatile group of bacteria with a wide range in virulence potential. To facilitate genome comparisons across this virulence spectrum, we present eight complete closed genome sequences of four S. enterica serotypes (Anatum, Montevideo, Typhimurium, and Newport) isolated from various cattle samples or from humans.