|Bosma, Wayne - Bradley University|
Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 8/20/2015
Publication Date: 8/20/2015
Citation: Appell, M., Bosma, W. 2015. Spectrofluorimetric study of the interaction of the mycotoxin citrinin with gold nanoparticles [abstract].
Technical Abstract: Citrinin is a nephrotoxic secondary metabolite produced by certain fungal species from the Aspergillus, Penicillium, and Monascus genera. Citrinin producing species occasionally contaminate grains, and may pose food safety risks. Analysis of this mycotoxin is frequently carried out by liquid chromatography-based fluorescence methods. Gold nanoparticles (AuNPs) offer a means to manipulate fluorescence detection and the materials provide a convenient platform for synthetic modification to tune emission signal. The influence of gold nanoparticles on the emission behavior of citrinin was investigated by steady-state fluorescence and ultraviolet absorption spectroscopy in polar and aprotic solvents. Fluorescence quenching of citrinin by gold nanoparticles was observed in neat solvent. However, the fluorescence quenching generally associated with gold nanoparticle interactions was completely overcome under strongly acidic conditions. This behavior provides a cost-effective alternative to tune citrinin detection.