Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 9/1/2015
Publication Date: 11/16/2015
Publication URL: http://handle.nal.usda.gov/10113/5203504
Citation: Maragos, C.M. 2015. Immunologically-based methods for detecting masked mycotoxins. In: Dall'Asta, C., Berthiller, F., editors. Masked Mycotoxins in Food: Formation, Occurrence and Toxicological Relevance. Issues in Toxicology, Book 24. London, UK: Royal Society of Chemistry. p. 32-49.
Technical Abstract: Masked mycotoxins are generally described as including unknown mycotoxins, non-extractable forms of known mycotoxins, or untargeted forms of known mycotoxins. Immunoassays can be developed with either broad cross-reaction to mycotoxin congeners or with high selectivity for a particular toxin. The result is that certain assays are able to detect masked mycotoxins along with the free (or ‘parent’) form, while others do not. This chapter summarizes the ability of reported immunoassays, commercial or otherwise, to detect or to isolate masked mycotoxins. In addition the basis for why certain immunoassays recognize masked mycotoxins, while others do not, is explored.