Location: Endemic Poultry Viral Diseases ResearchTitle: Heterotypic protection to infectious bronchitis virus Author
|Van Santen, Vicky|
Submitted to: American Association of Avian Pathologists
Publication Type: Abstract Only
Publication Acceptance Date: 4/1/2013
Publication Date: 7/28/2013
Citation: Toro, H., Yu, Q., van Santen, V., Joiner, K. 2014. Heterotypic protection to infectious bronchitis virus [abstract]. In: Proceedings of 2013 annual meeting of American Association of Avian Pathologists, July 20-23, 2013, Chicago, Illinois. CDROM, p.12. Interpretive Summary:
Technical Abstract: We developed Newcastle disease virus (NDV) LaSota (rLS) expressing a distinct spike (S) protein gene of infectious bronchitis virus (IBV). This recombinant vaccine technology confers cross-protection among different IBV strains. We also experimentally demonstrated that the recombinant construct maintains the biological properties of the parental NDV and provides complete protection against challenge with velogenic NDV.