Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 2/26/2012
Publication Date: N/A
Interpretive Summary: N/A
Technical Abstract: Dengue is the most important arbovirus of humans in the world. It is caused by one of four closely related virus serotypes whose primary vector is Aedes aegypti and secondarily by Ae. albopictus. A global dengue pandemic began in Southeast Asia after World War II and has intensified during the last 30 years. This presentation reviews the basic dengue virus transmission cycle in humans and focuses on the geographic spread of dengue and the increase of severe dengue (dengue hemorrhagic fever) internationally. It also reviews the expanding dengue problem in the Americas and reviews the major factors that have caused it to be recognized as a significant public health problem in the hemisphere. The response of international public health agencies to this situation will be presented including an effort to promote hemispheric eradication of Ae. aegypti. Current strategies for controlling dengue vectors will be discussed and will include traditional insecticide-based control methods as well as novel approaches that are emerging around the globe. The status of dengue vaccine development will also be reviewed.