Page Banner

United States Department of Agriculture

Agricultural Research Service


Location: Mycotoxin Prevention and Applied Microbiology Research

Title: Physicochemical study on interactions between T-2 and HT-2 toxin derivatives and cyclodextrins

item Ventrella, Andrea
item Longobardi, Francesco
item Agostiano, Angela
item Pascale, Michelangelo
item Lippolis, Vincenzo
item Maragos, Chris
item Catucci, Lucia

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 11/4/2011
Publication Date: 11/4/2011
Citation: Ventrella, A., Longobardi, F., Agostiano, A., Pascale, M., Lippolis, V., Maragos, C.M., Catucci, L. 2011. Physicochemical study on interactions between T-2 and HT-2 toxin derivatives and cyclodextrins. II European Conference on Cyclodextrins.

Interpretive Summary:

Technical Abstract: Physicochemical interactions occurring between fluorescent anthracene derivatives of T-2 and HT-2 toxins and different cyclodextrins (CDs) were investigated in aqueous solutions by means of UV-Vis absorption, fluorescence emission, and Dynamic Light Scattering. Binding constant values and physicochemical parameters were determined showing '-CDs to give the strongest inclusion reactions with both T-2 and HT-2 derivatives. Such interactions were found to be fundamentally enthalpy driven. Among '-CDs, dimethyl-'-CD (DIMEB) was found to induce the greatest fluorescence intensity enhancement. The findings of this work could be of great interest to improve mycotoxin detection by spectroscopic techniques

Last Modified: 10/16/2017
Footer Content Back to Top of Page