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ARS Home » Pacific West Area » Salinas, California » Crop Improvement and Protection Research » Research » Publications at this Location » Publication #263550

Title: Verticillium comparative genomics yields insights into niche adaptation by plant vascular wilt pathogens

Author
item Klosterman, Steven
item SUBBARAO, KRISHNA - UNIVERSITY OF CALIFORNIA
item KANG, SEOGCHAN - PENNSYLVANIA STATE UNIVERSITY
item VERONESE, PAOLA - NORTH CAROLINA STATE UNIVERSITY
item GOLD, SCOTT - UNIVERSITY OF GEORGIA
item THOMMA, BART - WAGENINGEN AGRICULTURAL UNIVERSITY
item CHEN, ZEHUA - BROAD INSTITUTE OF MIT/HARVARD
item HENRISSAT, BERNARD - UNIVERSITY OF THE MEDITERRANEAN
item LEE, YONG-HWAN - SEOUL NATIONAL UNIVERSITY
item PARK, JONGSUN - SEOUL NATIONAL UNIVERSITY
item GARCIA-PEDRAJAS, MARIA - CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
item BARBARA, DEZ - UNIVERSITY OF WARWICK
item Anchieta, Amy
item DE JONGE, RONNIE - WAGENINGEN UNIVERSITY AND RESEARCH CENTER
item SANTHANAM, PARTHA - WAGENINGEN UNIVERSITY AND RESEARCH CENTER
item MARUTHACHALAM, KARUNAKARAN - UNIVERSITY OF CALIFORNIA
item ATALLAH, ZAHI - UNIVERSITY OF CALIFORNIA
item AMYOTTE, STEFAN - AGRICULTURE AND AGRI-FOOD CANADA
item PAZ, ZAHI - UNIVERSITY OF GEORGIA
item INDERBITZIN, PATRIK - UNIVERSITY OF CALIFORNIA
item Hayes, Ryan
item HEIMAN, DAVID - BROAD INSTITUTE OF MIT/HARVARD
item YOUNG, SARAH - BROAD INSTITUTE OF MIT/HARVARD
item ZENG, QIANDONG - BROAD INSTITUTE OF MIT/HARVARD
item ENGELS, REINHARD - BROAD INSTITUTE OF MIT/HARVARD
item GALAGAN, JAMES - BROAD INSTITUTE OF MIT/HARVARD
item CUOMO, CHRISTINA - BROAD INSTITUTE OF MIT/HARVARD
item DOBINSON, KATHERINE - BROAD INSTITUTE OF MIT/HARVARD
item MA, LI-JUN - BROAD INSTITUTE OF MIT/HARVARD

Submitted to: Plant and Animal Genome Conference
Publication Type: Abstract Only
Publication Acceptance Date: 10/14/2010
Publication Date: 1/17/2011
Citation: Klosterman, S.J., Subbarao, K.V., Kang, S., Veronese, P., Gold, S.E., Thomma, B.J., Chen, Z., Henrissat, B., Lee, Y., Park, J., Garcia-Pedrajas, M.D., Barbara, D., Anchieta, A.G., De Jonge, R., Santhanam, P., Maruthachalam, K., Atallah, Z.K., Amyotte, S., Paz, Z., Inderbitzin, P., Hayes, R.J., Heiman, D.I., Young, S., Zeng, Q., Engels, R., Galagan, J., Cuomo, C., Dobinson, K.F., Ma, L. 2011. Verticillium comparative genomics yields insights into niche adaptation by plant vascular wilt pathogens. Plant and Animal Genome Conference. Online.

Interpretive Summary:

Technical Abstract: The vascular wilt fungi Verticillium dahliae and V. albo-atrum infect over 200 plant species worldwide, causing recurring crop losses estimated in the billions of dollars annually. Plant pathogenic Verticillium species are soilborne, and produce dormant structures that enable survival for years in the soil without a host. However, following germination, these pathogens infect and colonize the plant vascular system. To gain insights into the mechanisms that confer pathogenicity and proliferation in the unique ecological niche of the plant vascular system, the genomes of two Verticillium wilt pathogens were sequenced and compared to each other, and with the proteome of Fusarium oxysporum, another fungal vascular wilt pathogen. The analyses revealed that Verticillium spp. have an extraordinary capacity to degrade plant pectin, a capacity that may confer an ability to infect a broad range of plant hosts and to colonize plants systemically. The comparative studies further revealed a set of proteins that are conserved among all three wilt pathogens, including homologs of a bacterial glucosyl transferase with known roles in the synthesis of osmoregulated periplasmic glucans and pathogenicity. In addition, the high level of synteny between the two Verticillium genomes highlighted four lineage-specific regions in V. dahliae that are enriched in transposon sequences and particular gene families, features that may contribute to the increased genetic plasticity of V. dahliae. The study reveals insights into the niche adaptation of this group of agriculturally important plant pathogens, and sheds light on potential avenues for the development of novel disease management strategies.