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United States Department of Agriculture

Agricultural Research Service

Title: CHRONIC DISSEMINATED HISTOPLASMOSIS WITH PROLONGED LATENCY

Author
item Addidle, Michael
item Pynn, Joanne
item Skellern, Philippa
item Kasuga, Takao
item Grimwade, Kate

Submitted to: Journal of Internal Medicine
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/14/2010
Publication Date: 9/1/2010
Publication URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WJT-50BJNG8-4&_user=4421&_coverDate=09%2F30%2F2010&_rdoc=12&_fmt=high&_orig=browse&_srch=doc-info%28%23toc%236887%232010%23999389996%232265748%23FLA%23display%23Volume%29&_cdi=6887&_sort=d&_docanchor=&_ct=14&_acct=C000059598&_version=1&_urlVersion=0&_userid=4421&md5=2339984ea02e8a23c5902caf32217554
Citation: Addidle, M., Pynn, J., Skellern, P., Kasuga, T., Grimwade, K. 2010. CHRONIC DISSEMINATED HISTOPLASMOSIS WITH PROLONGED LATENCY. Journal of Internal Medicine. 61:272-274.

Interpretive Summary: Histoplasmosis is a disease caused by ascomycetous fungus Histoplasma capsulatum. We describe a case of chronic disseminated histoplasmosis. Evidence is presented to support a latency period of over sixty years between acquisition of infection and clinical manifestation. This is the longest latency period for histoplasmosis described in the medical literature to date.

Technical Abstract: A case of chronic disseminated histoplasmosis in an ex-serviceman is described. Evidence is presented to support a latency period of over sixty years between acquisition of infection and clinical manifestation. This is the longest latency period for histoplasmosis described in the medical literature to date. There is also a discussion relating to the association between military personnel and histoplasmosis.

Last Modified: 10/17/2017
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