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Title: Neolignans from the Leaves of Casearia sylvestris Swartz

Author
item WANG, WEI - University Of Mississippi
item ALI, ZULFIQAR - University Of Mississippi
item LI, XING-CONG - University Of Mississippi
item KHAN, IKHLAS - University Of Mississippi

Submitted to: Helvetica Chimica Acta
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/18/2009
Publication Date: 12/28/2009
Citation: Wang, W., Ali, Z., Li, X., Khan, I.A. 2009. Neolignans from the Leaves of Casearia sylvestris Swartz. Helvetica Chimica Acta. 93(1):139-146.

Interpretive Summary: Six new neolignans, casearialignans A-F (1-6) and one known lignan syringaresinol-ß-D-glucoside were isolated from the leaves of Casearia sylvestris. Here, we report the isolation and structure elucidation of the new neolignans.

Technical Abstract: Six new neolignans, casearialignans A-F (1-6) and one known lignan syringaresinol-ß-D-glucoside were isolated from the leaves of Casearia sylvestris. Their structures were determined on the basis of 1D and 2 D NMR and high resolution ESI-MS spectroscopic analyses. The relative and absolute configurations were determined by the value of coupling constant and CD spectral analysis respectively.