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ARS Home » Southeast Area » Stoneville, Mississippi » Warmwater Aquaculture Research Unit » Research » Publications at this Location » Publication #225583

Title: Nutritional Regulation of IGFs in Channel Catfish

item Peterson, Brian
item Waldbieser, Geoffrey - Geoff
item Small, Brian

Submitted to: Proceedings of International Congress on Biology of Fishes
Publication Type: Abstract Only
Publication Acceptance Date: 3/8/2008
Publication Date: 7/28/2008
Citation: Peterson, B.C., Waldbieser, G.C., Small, B.C. 2008. Nutritional Regulation of IGFs in Channel Catfish. Proceedings of International Congress on Biology of Fishes. P: 73

Interpretive Summary:

Technical Abstract: We examined changes in hepatic IGF-I and IGF-II mRNA, insulin like growth factor binding proteins (IGFBP-1 and IGFBP-2) mRNA, muscle IGF-I and IGF-II mRNA in fed (fed daily for 45 days) and restricted (not fed for 30 days followed by feeding for 15 days) channel catfish. By day 30, liver IGF-I mRNA decreased 14.3 fold compared to fed controls (P < 0.01). Abundance of IGFBP-1 mRNA increased (P < 0.05) 2.4 fold in restricted fish while IGFBP-2 mRNA was similar between treatments. Muscle IGF-II mRNA decreased (P < 0.05) 3.4 fold while levels of IGF-I mRNA were similar between treatments. After 15 days of refeeding, liver IGF-II mRNA was higher (P < 0.05) in restricted fish while all other genes were similar between treatments. A change in IGF-II mRNA due to restricted food intake suggests a physiological role for IGF-II in growth regulation of channel catfish.