Submitted to: American Chemical Society Symposium Series
Publication Type: Book / Chapter
Publication Acceptance Date: 10/1/2002
Publication Date: 5/1/2003
Citation: NAGLE, D.G., SULTANA, G.N., SCHRADER, K., HOSSAIN, C.F., STANIKUNAITE, R., HAMMAN, M.T., RAJBANDARI, I. SECONDARY METABOLITES FROM PLANTS AND MARINE ORGANISMS AS SELECTIVE ANTI-CYANOBACTERIAL AGENTS. AMERICAN CHEMICAL SOCIETY SYMPOSIUM SERIES. 2003. Interpretive Summary: Over one thousand extracts from plants found on land and from algae found in the ocean were tested for growth inhibition of the blue-green algae that causes the musty off-flavor in farm-raised channel catfish in Mississippi. Two compounds from a type of brown algae that grows in the ocean were found to selectively kill the musty blue-green algae and not kill a type of green algae that is the preferred type of algae in catfish aquaculture.
Technical Abstract: Extracts of more than one thousand species of plants and marine organisms were evaluated for selective algicidal activity against the musty-odor cyanobacterium (blue-green alga) Oscillatoria perornata. Bioassay-guided fractionation yielded anti-cyanobacterial compounds from the tropical marine brown alga Dictyota dichotoma. The structures of the active metabolites were confirmed spectroscopically to be two bicyclic diterpenes, 10-acetoxy-18-hydroxy-2,7-dolabelladiene and dictyol B acetate.