Research Project: Diagnostic and Mitigation Strategies to Control Tuberculosis in Cattle and Wildlife

Location: Infectious Bacterial Diseases Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Assessment of interferon-gamma response profiles after vaccination against bovine viral diarrhea virus (BVDV) as correlates of protection - (Peer Reviewed Journal)
Falkenberg, S., Dassanayake, R.P., Putz, E.J., Silvix, S., Crawford, L.S., Boggiatto, P.M. 2026. Assessment of interferon-gamma response profiles after vaccination against bovine viral diarrhea virus (BVDV) as correlates of protection. Veterinary Immunology and Immunopathology. https://doi.org/10.1016/j.vetimm.2026.111166.

Peripheral transcriptional responses to experimental SARS-CoV-2 inoculation in North American Elk cows and calves - (Peer Reviewed Journal)
Petry, B., Sarlo Davila, K.M., DeVries, A.C., Cassmann, E., Olsen, S.C., Boggiatto, P.M., Palmer, M.V., Putz, E.J. 2025. Peripheral transcriptional responses to experimental SARS-CoV-2 inoculation in North American Elk cows and calves. BMC Genomics. 26. Article 781. https://doi.org/10.1186/s12864-025-11956-5.

Permissiveness of American bison to infection with severe acute respiratory syndrome coronavirus-2 - (Peer Reviewed Journal)
Palmer, M.V., Devries, A.C., Cassmann, E.D., Olsen, S.C., Nielsen, D.W., Putz, E.J., Seger, H., Chandler, J.C., Boggiatto, P.M. 2025. Permissiveness of American bison to infection with severe acute respiratory syndrome coronavirus-2. Nature Scientific Reports. https://doi.org/10.1038/s41598-025-10100-3.

Tertiary lymphoid structures in pulmonary granulomas of cattle experimentally infected with aerosolized Mycobacterium bovis - (Peer Reviewed Journal)
Palmer, M.V., Jones, D.E., Bockenstedt, N.J., Boggiatto, P.M. 2025. Tertiary lymphoid structures in pulmonary granulomas of cattle experimentally infected with aerosolized Mycobacterium bovis. BMC Veterinary Research. 21. Article 403. https://doi.org/10.1186/s12917-025-04804-x.

Circulating foamy macrophages and other features of bacillus Calmette-Guérin challenge in Golden Syrian hamsters - (Peer Reviewed Journal)
Putz, E.J., Andreasen, C., Stasko, J.A., Hamond, C., Olsen, S.C., Nally, J.E., Palmer, M.V. 2025. Circulating foamy macrophages and other features of bacillus Calmette-Guérin challenge in Golden Syrian hamsters. Vaccine. 55. Article 127037. https://doi.org/10.1016/j.vaccine.2025.127037.

They don’t just go away: Demands and successes in combating persistent domestic diseases of food-producing livestock - (Abstract Only)

Oral delivery of bovine tuberculosis vaccine to free-ranging white-tailed deer - (Peer Reviewed Journal)
Vercauteren, K., Feuka, A., Lavelle, M., Glow, M., Kohen, K., Ryan, P., Aderman, A., Duffiney, A., Palmer, M.V., Boggiatto, P.M., Kanipe, C.R., Hamby, H., Ruell, E., Cosgrove, M., Vanderklok, M., Snow, N., Pepin, K., Campa Iii, H. 2025. Oral delivery of bovine tuberculosis vaccine to free-ranging white-tailed deer. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2025.1548627.

Differential expression of vascular endothelial growth factor A (VEGFA) and M1 macrophage marker nitric oxide synthase 2 (NOS2) in lymph node granulomas of BCG-vaccinated and non-vaccinated cattle infected with Mycobacterium - (Peer Reviewed Journal)
Kanipe, C.R., Putz, E.J., Palmer, M.V. 2025. Differential expression of vascular endothelial growth factor A (VEGFA) and M1 macrophage marker nitric oxide synthase 2 (NOS2) in lymph node granulomas of BCG-vaccinated and non-vaccinated cattle infected with Mycobacterium. Tuberculosis. https://doi.org/10.1016/j.tube.2025.102609.

Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG) - (Peer Reviewed Journal)
Palmer, M.V., Hwang, S., Kanipe, C.R., Putz, E.J., Fernandes, L., Didkowska, A., Boggiatto, P.M. 2025. Immune responses of cattle vaccinated by various routes with Mycobacterium bovis Bacillus Calmette-Guérin (BCG). BMC Veterinary Research. https://doi.org/10.1186/s12917-024-04452-7.

Induction of CD4 T cell memory responses following BCG vaccination in cattle - (Peer Reviewed Journal)
Sterle, H.M., Putz, E.J., Olsen, S.C., Boggiatto, P.M. 2024. Induction of CD4 T cell memory responses following BCG vaccination in cattle. Frontiers in Veterinary Science. 11. Article 1491424. https://doi.org/10.3389/fvets.2024.1491424.

Pathogen detection in early phases of experimental bovine tuberculosis - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Hwang, S., Thacker, T.C., Lehman, K.A., Ledesma, N.A., Gustafson, K., Boggiatto, P.M. 2024. Pathogen detection in early phases of experimental bovine tuberculosis. Veterinary Sciences. 11(8). Article 357. https://doi.org/10.3390/vetsci11080357.

Pathogen detection in early phases of experimental bovine tuberculosis - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Hwang, S., Thacker, T.C., Lehman, K.A., Ledesma, N.A., Gustafson, K.K., Boggiatto, P.M. 2024. Pathogen detection in early phases of experimental bovine tuberculosis. Veterinary Sciences. https://doi.org/10.3390/vetsci11080357.

Persistence of viral RNA in North American elk experimentally infected with an ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - (Peer Reviewed Journal)
Boggiatto, P.M., Buckley, A.C., Cassmann, E.D., Seger, H., Olsen, S.C., Palmer, M.V. 2024. Persistence of viral RNA in North American elk experimentally infected with an ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Scientific Reports. 14. Article 11171. https://doi.org/10.1038/s41598-024-61414-7.

Vaccination of white-tailed deer with Mycobacterium bovis bacillus calmette-guérin (BCG): effect of Mycobacterium avium ssp. paratuberculosis infection - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Lehman, K.A., Thacker, T.C., Putz, E.J., Boggiatto, P.M. 2023. Vaccination of white-tailed deer with Mycobacterium bovis bacillus calmette-guérin (BCG): effect of Mycobacterium avium ssp. paratuberculosis infection. Microorganisms. https://doi.org/10.3390/microorganisms11102488.

Wildlife immune responses to Mycobacterium bovis and to bacille of calmette-guerin - (Review Article)
Boggiatto, P.M., Kanipe, C.R., Putz, E.J., Olsen, S.C., Palmer, M.V. 2023. Wildlife immune responses to Mycobacterium bovis and to bacille of calmette-guerin. Journal of Immunology. https://doi.org/10.4049/jimmunol.2300323.

The devil you know and the devil you don’t: current status and challenges of bovine tuberculosis eradication in the United States - (Peer Reviewed Journal)
O'Brien, D.J., Thacker, T.C., Salvador, L.C., Duffiney, A.G., Robbe-Austerman, S., Camacho, M.S., Lombard, J.E., Palmer, M.V. 2023. The devil you know and the devil you don’t: current status and challenges of bovine tuberculosis eradication in the United States. Irish Veterinary Journal. https://doi.org/10.1186/s13620-023-00247-8.

Histopathologic differences in granulomas of BCG vaccinated and non-vaccinated cattle with bovine tuberculosis - (Peer Reviewed Journal)
Kanipe, C.R., Boggiatto, P.M., Putz, E.J., Palmer, M.V. 2022. Histopathologic differences in granulomas of BCG vaccinated and non-vaccinated cattle with bovine tuberculosis. Frontiers in Microbiology. 13, Article 1048648. https://doi.org/10.3389/fmicb.2022.1048648.

Mycobacterium bovis strain Ravenel is attenuated in cattle - (Peer Reviewed Journal)
Hadi, S.A., Brenner, E.P., Palmer, M.V., Waters, W.R., Thacker, T.C., Vilcheze, C., Larsen, M.H., Jacobs, W.R., Sreevatasan, S. 2022. Mycobacterium bovis strain Ravenel is attenuated in cattle. Pathogens. 11(11). Article 1330. https://doi.org/10.3390/pathogens11111330.

Pulmonary hamartoma in an elk calf (Cervus elaphus canadensis) - (Peer Reviewed Journal)
Boggiatto, P.M., Olsen, S.C., Palmer, M.V. 2022. Pulmonary hamartoma in an elk calf (Cervus elaphus canadensis). Journal of Veterinary Diagnostic Investigation. 35(2). https://doi.org/10.1177/10406387221141091.

SARS-CoV-2: Experimental studies on deer-to-deer transmission - (Abstract Only)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G., Boggiatto, P.M., Kanipe, C.R., Fernandes, M. 2022. SARS-CoV-2: Experimental studies on deer-to-deer transmission. United States Animal Health Association Proceedings. [Abstract}. https://doi.org/10.1371/journal.ppat.1010197.

From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer - (Peer Reviewed Journal)
Martins, M., Boggiatto, P.M., Buckley, A., Cassmann, E.D., Falkenberg, S.M., Caserta, L.C., Fernandes, M.H., Kanipe, C.R., Lager, K.M., Palmer, M.V., Diel, D.G. 2022. From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in highly susceptible white-tailed deer. PLoS Pathogens. 18(3). Article e1010197. https://doi.org/10.1371/journal.ppat.1010197.

The bovine tuberculoid granuloma - (Review Article)
Palmer, M.V., Kanipe, C.R., Boggiatto, P.M. 2022. The bovine tuberculoid granuloma. Pathogens. 11(1). Article 61. https://doi.org/10.3390/pathogens11010061.

Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 - (Proceedings)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Biocontainment Network Monthly Scientific Seminar. 95(11):e00083-21 Meeting Abstract. https://doi.org/10.1128/JVI.00083-21.