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ARS Home » Northeast Area » Wyndmoor, Pennsylvania » Eastern Regional Research Center » Sustainable Biofuels and Co-products Research » Research » Research Project #427752

Research Project: Commercial Products from Microbial Lipids

Location: Sustainable Biofuels and Co-products Research

Project Number: 8072-41000-099-00-D
Project Type: In-House Appropriated

Start Date: May 19, 2015
End Date: May 19, 2020

Objective 1: Enable commercial processes for converting microbial lipids and the byproducts of their fermentation into marketable products. Sub-objective 1: Production of microbial glycolipids and variants to enhance commercial viability. 1A: Genetic engineering of P. chlororaphis for production of RL from low-cost bioglycerol and soy-sugar byproduct. 1B: Fermentative production of short-chain (C=12) and very-long-chain (C22) sophorolipids. Sub-objective 2: Synthesis and testing of value-added products from glycolipids and components. Enabling chemical and/or enzymatic production of glycolipid components and testing products as novel antimicrobial agents and novel sugar substitutes.

To enhance the commercial viability of microbial glycolipids (i.e., sophorolipids, SLs; and rhamnolipids, RLs), their high-value antimicrobial property will be extensively researched in this project for full exploitation in end-user industrial applications. Accordingly, the structure-function relationship of the antimicrobial activity of these glycolipids will be established by first biosynthesizing various structurally varied glycolipids through the use of new producing strains and uniquely synthesized oleochemicals from fats and oils as fermentative feedstocks. The resultant microbial SLs containing very-long-chain (C22) and short-chain (C