Author
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Klevay, Leslie |
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Submitted to: Book Chapter
Publication Type: Book / Chapter Publication Acceptance Date: 4/1/2000 Publication Date: N/A Citation: N/A Interpretive Summary: Ischemic heart disease is the leading cause of death in the U.S. Its origin is unknown, but a multitude of dietary factors have been implicated. The Western diet is closely associated with heart disease risk. This diet is high in fat and has other characteristics that may modify risk. Several trace elements are offered as answers to the important question "what determines who lives long and who dies early of ischemic heart disease?" when people consume the Western diet for a lifetime. Copper receives emphasis here over magnesium, selenium and iron because those elements have received attention elsewhere and because diets low are easily accessible to people in the U.S. Animals deficient in copper have many anatomical, chemical and physiological similarities to people with ischemic heart disease. Experiments with animals or clinical studies with other dietary components have not produced abnormalities such as bone disease, glucose intolerance, high blood pressure, low heart copper or high uric acid, etc. found in people with ischemic heart disease and animals deficient in copper. Technical Abstract: Ischemic heart disease is the leading cause of death in the U.S. Its origin is unknown, but a multitude of dietary factors have been implicated. The Western diet is closely associated with heart disease risk. This diet is high in fat and has other characteristics that may modify risk. Several trace elements are offered as answers to the important question "what determines who lives and who dies early of ischemic heart disease?" when people consume the Western diet for a lifetime. Copper receives emphasis here over magnesium, selenium and iron because those elements have received attention elsewhere and because diets low are easily accessible to people in the U.S. Animals deficient in copper have many anatomical, chemical and physiological similarities to people with ischemic heart disease. Experiments or clinical studies with other dietary components have not produced abnormalities such as bone disease, glucose intolerance, high blood pressure, low heart copper or high uric acid, etc. |
