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ARS Home » Plains Area » Fargo, North Dakota » Edward T. Schafer Agricultural Research Center » Cereal Crops Research » Research » Publications at this Location » Publication #380536

Research Project: Improvement of Biotic Stress Resistance in Durum and Hard Red Spring Wheat Using Genetics and Genomics

Location: Cereal Crops Research

Title: Draft genome sequence of Streptomyces sp. HB-N217 isolated from the marine sponge Forcepia sp.

item XAVIER, RENE - Florida Atlantic University
item XU, DONGBO - Florida Atlantic University
item MCCARTHY, PETER - Florida Atlantic University
item Yang, Shengming
item WANG, GUOJUN - Florida Atlantic University

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/30/2021
Publication Date: 2/25/2021
Citation: Xavier, R.K., Xu, D., McCarthy, P., Yang, S., Wang, G. 2021. Draft genome sequence of Streptomyces sp. HB-N217 isolated from the marine sponge Forcepia sp.. Microbiology Resource Announcements. 10. Article e01410-20.

Interpretive Summary: Natural products produced by bacteria actinomycetes provide a rich source of drugs, antibiotics and fungicides. However, the identification of novel products and their application potential from actinomycetes is limited due to relatively few genome sequences being deciphered. In the present study, we determined the complete genome sequence for strain HB-N217, which was collected at the Gulf of Mexico. Molecular analysis revealed more than 30 biosynthetic gene clusters involved in secondary metabolite production. Therefore, these results provided useful information and a potential resource for pharmacists, biochemists, and pathologists to identify valuable natural products, as well as for geneticists to conduct diversity and association studies.

Technical Abstract: The Gram-positive bacterium Streptomyces sp. HB-N217 was isolated from a Gulf of Mexico sponge Forcepia sp. Here, we reported the draft genome sequence, with a genome size of approximately 8.1 Mb and a G+C content of 71.8%. The genome sequences revealed a rich presence of biosynthetic gene clusters that bear the capability to produce secondary metabolites. The results will also aid marine natural product chemistry and sponge-microbe association studies.