Location: Virus and Prion ResearchTitle: Comparative virulence and genomic analysis of streptococcus suis isolates
|WAACK, URSULA - Oak Ridge Institute For Science And Education (ORISE)|
|HAU, SAMANTHA - Oak Ridge Institute For Science And Education (ORISE)|
Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/19/2020
Publication Date: N/A
Technical Abstract: Streptococcus suis is a bacterial swine pathogen causing substantial economic and health burdens to the pork industry. Mechanisms used by S. suis to colonize and cause disease remain unknown and vaccines and/or intervention strategies currently do not exist. Studies addressing virulence mechanisms used by S. suis have been complicated because different isolates can cause a spectrum of disease outcomes ranging from lethal systemic disease to asymptomatic carriage. The objectives of this study were to perform comparative genomic analyses of S. suis isolates that exhibit different pathogenic capacities to identify genomic attributes associated with virulent phenotypes.