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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Publications at this Location » Publication #374999

Research Project: Intervention Strategies to Control Endemic and New and Emerging Viral Diseases of Swine

Location: Virus and Prion Research

Title: Comparative virulence and genomic analysis of streptococcus suis isolates

item WAACK, URSULA - Oak Ridge Institute For Science And Education (ORISE)
item Anderson, Tavis
item HAU, SAMANTHA - Oak Ridge Institute For Science And Education (ORISE)
item Brockmeier, Susan
item Shore, Sarah
item Bayles, Darrell
item Nicholson, Tracy

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/19/2020
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Streptococcus suis is a bacterial swine pathogen causing substantial economic and health burdens to the pork industry. Mechanisms used by S. suis to colonize and cause disease remain unknown and vaccines and/or intervention strategies currently do not exist. Studies addressing virulence mechanisms used by S. suis have been complicated because different isolates can cause a spectrum of disease outcomes ranging from lethal systemic disease to asymptomatic carriage. The objectives of this study were to perform comparative genomic analyses of S. suis isolates that exhibit different pathogenic capacities to identify genomic attributes associated with virulent phenotypes.