Submitted to: Data in Brief
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/26/2020
Publication Date: 6/30/2020
Citation: Reinhardt, T.A., Lippolis, J.D. 2020. Dataset of bovine mammary gland dry secretion proteome from the end of lactation through day 21 of the dry period. Data in Brief. https://doi.org/10.1016/j.dib.2020.105954.
Interpretive Summary: The dry period is critical to the success of the subsequent lactation for many reasons. Of particular importance is the rate of establishment of new mastitis infection is greater in the dry period than in lactation. Mastitis susceptibility is greatest in the first few weeks of the dry period. Though there are both physical and mechanical reasons for increased Mastitis susceptibility in the first few weeks of the dry period, we know from the work of others that dry secretions have high levels of antimicrobial proteins and bacterial growth is diminished in dry secretions compared to milk. However, we found that by day 21 of the dry period proteins such as lactoferrin no longer correlated with reduced bacterial growth in dry secretions. The establishment of a dry secretion proteome for the first 3 weeks of the dry period is the start of a library of information to better understand this critical period in dairy cow management. The dataset in this mansuscript presents all the raw data in a format that other Dairy Scientist may use for their research.
Technical Abstract: This dataset is a label free quantification of proteins milk and dry secretions from the end of lactation through day 21 of the dry period using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The data supplied in this article supports the accompanying publication entitled “Characterization of Bovine Dry Secretions and their Proteome from the End of Lactation Through Day 21 of the Dry Period” . The Thermo mass spectrometry raw file data and MaxQuant files have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset number PXD017837.