Location: Plant, Soil and Nutrition ResearchTitle: Ripening activator turned repressor
Submitted to: Nature Plants
Publication Type: Review Article
Publication Acceptance Date: 10/29/2017
Publication Date: 11/13/2017
Citation: Giovannoni, J.J. 2017. Ripening activator turned repressor. Nature Plants. 3:920-921. doi.org/10.1038/s41477-017-0062-0
Technical Abstract: Gene editing reveals the tomato ripening-inhibitor (rin) mutation encodes an active repressor of ripening, refines our understanding of RIN function and highlights strategies for engineering shelf-life control. While RIN has long been touted as a central regulator of ripening, its function for ripening is not as absolute as previously thought, as rin confers a gain of repression activity rather than loss of function. Nevertheless, the distinct and significant inhibition of ripening observed in the gene edited RIN knock-outs reaffirms RIN as a critical component of ripening control.