Location: Virus and Prion ResearchTitle: Draft genome sequences of 9 LA-MRSA ST5 isolates obtained from humans after short term swine contact
|HAU, SAMANTHA - Iowa State University|
|FRANA, TIMOTHY - Iowa State University|
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 9/1/2017
Publication Date: 10/12/2017
Citation: Hau, S.J., Bayles, D.O., Alt, D.P., Frana, T.S., Nicholson, T.L. 2017. Draft genome sequences of nine livestock-associated methicillin-resistant Staphylococcus aureus sequence type 5 isolates obtained from humans after short-term swine contact. Genome Announcements. 5(41):e01080-17.
Interpretive Summary: In the United States, swine harbor a mixed population of livestock associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates with the sequence type (ST) 398, ST9, and ST5 lineages being detected. LA-MRSA ST5 isolates are particularly concerning to the public health community because, while the ST398 and ST9 lineage are considered livestock adapted and are thought to be less able to colonize and cause disease in humans, the ST5 lineage is globally disseminated and a significant cause of disease in both the hospital and community setting. Here, we report draft genome sequences for 9 LA-MRSA ST5 isolates obtained from humans after short term swine contact. This information can be directly used to search for mobile genetic elements encoding virulence or host-adapted genes. This information is important to public health professional, veterinarians, producers, and consumers.
Technical Abstract: Livestock associated methicillin resistant Staphylococcus aureus (LA-MRSA) sequence type 5 have raised concerns surrounding the potential for these isolates to colonize or cause disease in humans with swine contact. Here, we report draft genome sequences for 9 LA-MRSA ST5 isolates obtained from humans after short term swine contact.