Location: Virus and Prion ResearchTitle: Bordetellosis
Submitted to: Diseases of Swine
Publication Type: Book / Chapter
Publication Acceptance Date: 8/7/2017
Publication Date: N/A
Technical Abstract: This chapter, entitled "Bordetellosis", will be included in the 11th Edition of Diseases of Swine, and reviews the etiology, public health significance, epidemiology, pathogenesis, clinical signs, lesions, diagnosis, immunity, and prevention and control of diseases caused by Bordetella bronchiseptica (Bb). In swine, Bb is widespread and plays multiple roles in respiratory disease. It is the primary etiologic agent of nonprogressive atrophic rhinitis, a mild-to-moderately severe, reversible condition. Nasal colonization by Bb also promotes colonization by toxigenic strains of Pasteurella multocida, which leads to severe, progressive atrophic rhinitis. In young pigs, Bb is a primary cause of bronchopneumonia and in older pigs contributes to the porcine respiratory disease complex. In addition to P. multocida, Bb enhances colonization of other swine bacterial pathogens such as Streptococcus suis and Haemophilus parasuis and increases the severity of respiratory disease associated with common swine respiratory viruses, including porcine reproductive and respiratory syndrome virus and swine influenza virus.