Location: Aquatic Animal Health ResearchTitle: Complete genome sequence of the fish pathogen Flavobacterium columnare strain C#2
|BARTELME, RYAN - University Of Wisconsin|
|NEWTON, RYAN - University Of Wisconsin|
|ZHU, YONGTAO - University Of Wisconsin|
|LI, NAN - Chinese Academy Of Sciences|
|MCBRIDE, MARK - University Of Wisconsin|
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/13/2016
Publication Date: 6/23/2016
Citation: Bartelme, R.P., Newton, R.J., Zhu, Y., Li, N., Lafrentz, B.R., Mcbride, M.J. 2016. Complete genome sequence of the fish pathogen Flavobacterium columnare strain C#2. Genome Announcements. 4(3):e00624-16. doi:10.1128/genomeA.00624-16.
Interpretive Summary: Columnaris disease of freshwater fish is caused by infection with the bacterium Flavobacterium columnare. It is one of the most prevalent diseases in the catfish industry contributing to losses for producers and this disease has emerged as a significant problem for the rainbow trout industry. In this manuscript, researchers describe the complete genome sequence of a virulent strain of F. columnare. The availability of complete genome sequence data and the ability to genetically manipulate this strain of F. columnare will allow for experiments to identify how this bacterium causes disease in fish. This knowledge is important for developing new methods for the prevention and control of columnaris disease.
Technical Abstract: Flavobacterium columnare is a Gram-negative bacterial pathogen that causes columnaris disease of freshwater fish. Flavobacterium columnare strain C#2 was isolated from a diseased warm water fish and is typed as genomovar II. The genome consists of a single 3.33 Mb circular chromosome with 2,689 predicted coding genes.