Submitted to: Seminars in Cell and Developmental Biology
Publication Type: Review Article
Publication Acceptance Date: 5/20/2016
Publication Date: 5/20/2016
Citation: Underwood, W. 2016. Contributions of host cellular trafficking and organization to the outcomes of plant-pathogen interactions. Seminars in Cell and Developmental Biology. 56:163-173.
Interpretive Summary: The plant antimicrobial immune system is comprised of immune receptors that collectively provide cellular surveillance to detect the presence of potentially pathogenic microorganisms and initiate appropriate defense responses to combat infection. The struggle between prospective pathogens and the plant immune system involves dynamic cellular processes that ultimately dictate the outcome of the interaction, resistance or infection. Many filamentous plant pathogens parasitize their hosts through specialized infection structures, requiring the co-option of plant membrane trafficking processes to build and accommodate these structures. In resistant interactions, plant membrane trafficking plays a pivotal role in the delivery of defenses to the site of interaction with the invading microorganism. This article highlights recent research into cell biological aspects of plant-microbe interactions.
Technical Abstract: In recent years it has become increasingly apparent that dynamic changes in protein localization, membrane trafficking pathways, and cellular organization play a major role in determining the outcome of interactions between plants and pathogenic microorganisms. Plants have evolved sophisticated perception systems to recognize the presence of potentially pathogenic microorganisms via the detection of non-self or modified-self elicitor molecules, pathogen virulence factors, or the activities of such virulence factors. Dynamic cellular processes and trafficking pathways play pivotal roles in detection and signaling by plant immune receptors and are vital for the execution of spatially targeted defense responses to thwart invasion by potential pathogens. Conversely, from the perspective of the pathogen, the ability to manipulate plant cellular organization and trafficking processes to establish infection structures and deliver virulence factors is a major determinant of pathogen success. This review summarizes our current understanding of how dynamic cellular processes shape the outcomes of diverse plant-pathogen interactions and addresses ways in which our rapidly expanding knowledge of the cell biological processes that contribute to immunity or infection may influence efforts to improve plant disease resistance.