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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Immunity and Disease Prevention Research » Research » Publications at this Location » Publication #323858

Title: Vitamin A and Epigenetic Modifications

item Stephensen, Charles

Submitted to: Sight and Life Newsletter
Publication Type: Trade Journal
Publication Acceptance Date: 11/4/2015
Publication Date: 12/22/2015
Citation: Stephensen, C.B. 2015. Vitamin A and Epigenetic Modifications. Sight and Life Newsletter. Vol.29(2) Pg 21-23.

Interpretive Summary: Vitamin A supplementation is recommended in many countries for young children 6 m to 5 y of age to decrease the risk of death from infectious diseases. Recent research results have suggested that such supplementation may be less beneficial now than when this policy was first introduced, due to changes in the nutritional status in populations covered by the policy. In addition, new research findings in cell culture studies suggest that there might be adverse effects with vitamin A supplementation to infants receiving certain vaccines. This commentary discusses the varied effects of vitamin A on immune function in such cell culture systems as well as the difficulty of predicting specific effects of vitamin A supplementation on immune function in human studies.

Technical Abstract: NONE