Author
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Neill, John |
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 11/6/2014 Publication Date: 12/11/2014 Publication URL: http://handle.nal.usda.gov/10113/61331 Citation: Neill, J.D. 2014. Complete genome sequence of the San Miguel sea lion virus-8 reveals that it is not a member of the vesicular exanthema of swine virus/San Miguel Sea Lion virus species of the Caliciviridae. Genome Announcements. 2(6). e01286-14. DOI: 10.1128/genomeA.01286-14. Interpretive Summary: The San Miguel sea lion viruses (SMSV) are caliciviruses that were isolated from marine pinnepeds, many associated with vesicular lesions. Due to their relatedness to vesicular exanthema of swine viruses (VESV) that have been eradicated in the United States, there is a need to characterize the SMSV and to monitor domestic livestock for their presence. Here, the genomic RNA sequence of SMSV-8 was determined. This analysis revealed that SMSV-8 is genetically distinct from the other members of the SMSV group and probably constitutes a novel genus within the Caliciviridae. This supports earlier reports that SMSV-8 did not react to immunologic or genetic (PCR) analysis. The authors of these reports suggested that SMSV-8 did not belong to the SMSV group of viruses. Technical Abstract: The complete genome sequence of the San Miguel sea lion virus-8 (SMSV-8) was determined. Comparison of this sequence to other calicivirus sequences in GenBank showed that this virus was genetically distinct from the VESV/SMSV viruses and belonged to a novel clade within the Vesivirus genus. |