Submitted to: Standards in Genomic Sciences
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 10/29/2014
Publication Date: 12/8/2014
Publication URL: http://handle.nal.usda.gov/10113/61545
Citation: Zehr, E.S., Bayles, D.O., Boatwright Jr, W.D., Tabatabai, L.B., Register, K.B. 2014. Complete genome sequence of Ornithobacterium rhinotracheal strain ORT-UMN 88. Standards in Genomic Sciences. 9:16. DOI: 10.1186/1944-3277-9-16.
Interpretive Summary: This the complete sequence of the genetic material of a bacterium, Ornithobacterium rhinotracheale, which causes respiratory disease in poultry (strain ORT-UMN 88). This report comprises results from the first of two types of the bacterium that have been identified. The disease results in economic losses to the poultry industry, including reduced egg production and hatchability in breeder flocks as well as reduced weight gain, increased mortality, and increased condemnation rates. By studying the genes of this bacterium, researchers may be able to find ways to develop vaccines to control the disease, which should result in fewer losses for poultry producers.
Technical Abstract: Ornithobacterium rhinotracheale (O. rhinotracheale) strain ORT-UMN 88 is a Gram-negative pleomorphic rod-shaped bacterium and an etiologic agent of pneumonia and airsacculitis in poultry. It is a member of the family Flavobacteriaceae of the phylum Bacteroidetes. O. rhinotracheale strain ORT-UMN 88 was isolated from the pneumonic lung of a turkey in 1995. It was the isolate first used to experimentally reproduce disease in turkeys and has since been the focus of investigations characterizing potential virulence factors of the bacterium. The genome of O. rhinotracheale strain ORT-UMN 88 consists of a circular chromosome of 2,397,867 bp with a total of 2300 protein-coding genes, nine RNA genes, and one noncoding RNA gene. A companion paper in this issue of SIGS reports the draft genome sequence of an additional strain of O. rhinotracheale, isolated in 2006.