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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #298244

Title: Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia

Author
item Hauglund, Melissa
item Tatum, Fred
item Bayles, Darrell
item Maheswaran, Samuel
item Briggs, Robert - Bob

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 9/25/2013
Publication Date: 10/17/2013
Citation: Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2013. Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia. Genome Announcements. 1(5). DOI: 10.1128/genomeA.00848-13.

Interpretive Summary: The bacterium Mannheimia haemolytica is a prominent and costly cause of respiratory disease in domestic cattle. During periods of stress or concurrent respiratory viral infection some serotypes of the bacterium proliferate dramatically, increasing the odds of progression to pneumonic disease. The genomes of two isolates which exhibit dramatic proliferation were sequenced to facilitate molecular characterization of the phenomenon and the potential development of novel disease control methods.

Technical Abstract: Here we report two genomes, one complete and one draft, from virulent bovine strains of Mannheimia haemolytica serotype A1 recovered prior to the field usage of modern antimicrobial drugs.