Location: Warmwater Aquaculture Research UnitTitle: Complete genome sequence of channel catfish epidemic isolate Aeromonas hydrophila ML09-119) Author
|Waldbieser, Geoffrey - Geoff|
|Schroeder, Steven - Steve|
Submitted to: Genome Announcements
Publication Type: Peer reviewed journal
Publication Acceptance Date: 8/21/2013
Publication Date: 9/19/2013
Citation: Tekedar, H., Waldbieser, G.C., Karsi, A., Liles, M., Griffin, M., Vamenta, S., Sonstegard, T.S., Hossain, M., Schroeder, S.G., Khoo, L., Lawrence, M. 2013. Complete genome sequence of channel catfish epidemic isolate Aeromonas hydrophila ML09-119. Genome Announcements. 1(5):e00755-13. Interpretive Summary: Virulent strains of the bacteria Aeromonas hydrophila have been implicated in severe disease outbreaks in commercial catfish culture, leading to rapid and substantial losses of large catfish in affected ponds. A team of scientists from Mississippi State University, Auburn University, and USDA-ARS-Warmwater Aquaculture Research Unit used first- and second- generation DNA sequencing technologies to produce a reference genome sequence assembly of the virulent ML09-119 strain of A. hydrophila. Compared with a reference strain of A. hydrophila, this virulent strain contains genomic regions that encode loci involved in prophage structure and regulation that may affect its virulence. The availability of the ML09-119 genome sequence permits sophisticated investigations that will determine virulence factors and will support research to develop diagnostics and therapeutants to reduce production losses due to A. hydrophila infection.
Technical Abstract: Aeromonas hydrophila is a Gram-negative, rod-shaped, mesophilic bacteria that infects both aquatic poikilothermic animals and mammals, including humans. Here, we present the complete genome sequence of Aeromonas hydrophila ML-09-119, which represents a clonal group of A. hydrophila isolates causing outbreaks of bacterial septicemia in channel catfish since 2009.