|Nielsen, Forrest - Frosty|
|Poellot, Rhonda Lee|
Submitted to: Workshop Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 9/1/2004
Publication Date: 11/1/2004
Citation: Nielsen, F.H., Poellot, R.A. 2004. Boron status affects differences in blood immune cell populations in rats fed diets containing fish oil or safflower oil. In: Anke, M., Flachowsky, G., Kisters, K., et. al. editors. Proceedings of Macro and Trace Elements 22nd Workshop, September 24-25, 2004, Jena, Germany. p. 959-964. Interpretive Summary:
Technical Abstract: Numerous studies have demonstrated that the immune cell inflammatory response is influenced by diets with different fatty acid compositions. Diets rich in n-6 polyunsaturated fatty acids (PUFAs) have generally been shown to enhance the inflammatory response, while diets rich in n-3 PUFAs have been shown to be anti-inflammatory (Thies et al, 2001). Much of this difference in response is thought to be caused by changes in immune cell membrane composition, which results in the production of different eicosanoid types and amounts, thus altering membrane fluidity that can affect intercellular interaction, receptor expression, nutrient transport and signal transduction (Kelley, 2001).