Research Project: Utilizing Precision Approaches to Refine Dietary Guidance of Americans to Reduce Chronic Disease

Location: Obesity and Metabolism Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Total oxylipin concentrations in NIST SRM 1950 plasma compared to fresh and commercially obtained human plasma - (Peer Reviewed Journal)
Kampschulte, N., Scholz, L., Pedersen, T.L., Snodgrass, I.F., Newman, J.W., Schebb, N.H. 2026. Total oxylipin concentrations in NIST SRM 1950 plasma compared to fresh and commercially obtained human plasma. Journal of Lipid Research. 64(4). https://doi.org/10.1016/j.jlr.2026.101011.

The rate of cortisol decline after consuming a high-fat test meal for breakfast partially explained sex-dependent variation in post ingestive cardiovascular status - (Peer Reviewed Journal)
Laugero, K.D., Snodgrass, R.G., Keim, N.L. 2026. The rate of cortisol decline after consuming a high-fat test meal for breakfast partially explained sex-dependent variation in post ingestive cardiovascular status. Current Developments in Nutrition. 10(3). https://doi.org/10.1016/j.cdnut.2026.107655.

Genetic determinants of BMI, diet, and fitness interact to partially explain anthropometric obesity traits but not the metabolic consequences of obesity in men and women - (Peer Reviewed Journal)
Arrington, C.E., Tacad, D.M., Allayee, H., Sutton, K.J., Dombrowski, C., Keim, N.L., Newman, J.W., Bennett, B.J. 2026. Genetic determinants of BMI, diet, and fitness interact to partially explain anthropometric obesity traits but not the metabolic consequences of obesity in men and women. International Journal of Obesity. https://doi.org/10.1038/s41366-026-02027-0.

Metabolic alteration in oxylipins and endocannabinoids point to an important role for soluble epoxide hydrolase and inflammation in Alzheimer’s disease—finding from Alzheimer’s Disease Neuroimaging Initiative - (Peer Reviewed Journal)
Borkowski, K., Yin, C., Kindt, A., Liang, N., De Lange, E., Blach, C., Newman, J.W., Kaddurah-Daouk, R., Hankemeier, T. 2026. Metabolic alteration in oxylipins and endocannabinoids point to an important role for soluble epoxide hydrolase and inflammation in Alzheimer’s disease—finding from Alzheimer’s Disease Neuroimaging Initiative. Alzheimer's Research & Therapy. 18(21). https://doi.org/10.1186/s13195-025-01939-9.

Type 2 diabetes mellitus, cognitive performance, and incident dementia; identifying mediating pathways and biomarkers from the plasma proteome - (Peer Reviewed Journal)
Perfetto, S.E., Ruthirakuhan, M., Ryoo, S.W., Wong, Y.Y., Xiong, L.Y., Anita, N.Z., Caveney, N., Edgar, L., Newman, J.W., Cogo-Moreira, H., Swardfager, W. 2025. Type 2 diabetes mellitus, cognitive performance, and incident dementia; identifying mediating pathways and biomarkers from the plasma proteome. Journal of Neurochemistry. 169(12). https://doi.org/10.1111/jnc.70306.

FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - (Peer Reviewed Journal)
Lange, M., Wölk, M., Li, V., Doubravsky, C.E., Hendricks, J.M., Kato, S., Otoki, Y., Styler, B., Johnson, S., Harris, A., Nakagawa, K., Snodgrass, I.F., Kim, D., Newman, J.W., Fedorova, M., Olzmann, J.A. 2025. FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis. Nature Cell Biology. 27:1902-1913. https://doi.org/10.1038/s41556-025-01790-y.

A cross-sectional study of macronutrients, vitamins, minerals, and bioactive components in human milk of approved milk bank donors from low-, middle-, and high-income countries - (Peer Reviewed Journal)
Perrin, M.T., Mansen, K., Israel-Ballard, K., Bode, L., Hampel, D., Shahab-Ferdows, S., Allen, L.H., Maggio, F., Njuguna, E., Tran, H.T., Wesolowska, A. 2025. A cross-sectional study of macronutrients, vitamins, minerals, and bioactive components in human milk of approved milk bank donors from low-, middle-, and high-income countries. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2025.07.031.

Trimethylamine- N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability - (Peer Reviewed Journal)
Cheng, J., Cheng, M., Sinha, S., Cely, I., Gladkikh, S., Han, M.T., Zhang, G., Zhou, Z., Chugh, R., Ahn, I., Diamante, G., Wang, Y., Wang, Z., Bennett, B.J., Cai, H., Allayee, H., Hazen, S., Lusis, A.J., Shih, D.M., Yang, X. 2025. Trimethylamine- N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability. Arteriosclerosis Thrombosis and Vascular Biology. 45(10): 1784 - 1798. https://doi.org/10.1161/ATVBAHA.125.323047.

Neglected micronutrients – considering a broader set of vitamins and minerals in public health nutrition programs worldwide: A narrative review - (Peer Reviewed Journal)
Brown, K., Hess, S.Y., Moore, S.E., Combs, Jr., G.F., Kashman, K., McNulty, H., Allen, L.H., Krebs, N.F., Pfeiffer, C.M., Rybak, M.E., Osendarp, S.J. 2025. Neglected micronutrients – considering a broader set of vitamins and minerals in public health nutrition programs worldwide: A narrative review. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2025.06.030.

The impact of holder pasteurization on macronutrients, vitamins, minerals, and bioactive factors in human milk processed in a milk bank setting - (Peer Reviewed Journal)
Davis, A., Lee, S., Hampel, D., Shahab-Ferdows, S., Allen, L.H., Bode, L., Mansen, K., Israel-Ballard, K., Perrin, M.T. 2025. The impact of holder pasteurization on macronutrients, vitamins, minerals, and bioactive factors in human milk processed in a milk bank setting. Current Developments in Nutrition. 9(8). Article 107490. https://doi.org/10.1016/j.cdnut.2025.107490.

Hypertension and the gut microbiome: A science advisory from the American Heart Association - (Peer Reviewed Journal)
Yang, T., Maki, K.A., Marques, F.Z., Cai, J., Joe, B., Pipine, C.J., Pluznick, J.L., Meyer, K.A., Kirabo, A., Bennett, B.J. 2025. Hypertension and the gut microbiome: A science advisory from the American Heart Association. Hypertension. https://doi.org/10.1161/HYP.0000000000000247.

Protocol: The International Milk Composition (IMiC) Consortium - a harmonized secondary analysis of human milk from four studies - (Peer Reviewed Journal)
Fehr, K., Mertens, A., Shu, C., Dailey-Chwalibog, T., Shenhav, L., Allen, L.H., Beggs, M.R., Bode, L., Chooniedass, R., DeBoer, M.D., Deng, L., Espinosa, C., Hampel, D., Jahual, A., Jehan, F., Jain, M., Kolsteren, P., Kawle, P., Lagerborg, K., Manus, M., Mataraso, S., McDermid, J.M., Muhammad, A., Peymani, P., Pham, M., Shahab-Ferdows, S., Shafiq, Y., Subramoney, V., Sunko, D., Toe, L.C., Turvey, S., Xue, L., Rodriguez, N., Hubbard, A., Aghaeepour, N., Azad, M.B. 2025. Protocol: The International Milk Composition (IMiC) Consortium - a harmonized secondary analysis of human milk from four studies. Frontiers in Nutrition. 12. Article 1548739. https://doi.org/10.3389/fnut.2025.1548739.

Technical requirements for LC-MS/MS oxylipin analysis - (Other)
Schebb, N.H., Kampschulte, N., Hagn, G., Plitzko, K., Meckelmann, S.W., Ghosh, S., Joshi, R., Kuligowski, J., Vuckovic, D., Botana, M.T., Sánchez-Illana, Á., Zandkarimi, F., Das, A., Yang, J., Schmidt, L., Checa, A., Roche, H.M., Armando, A.M., Edin, M.L., Lih, F.B., Henao, J., Miyamoto, S., Giuffrida, F., Moussaieff, A., Domingues, R., Rothe, M., Hinz, C., Das, U.S., Rund, K.M., Taha, A., Hofstetter, R.K., Werner, M., Kahnt, A., Bertrand-Michel, J., Le Faouder, P., Gurke, R., Thomas, D., Torta, F., Biagini, D., Idborg, H., Lomonaco, T., Liu, J., Fedorova, M., Barden, A., Mori, T.A., Kennedy, P., Maxey, K., Ivanisevic, J., Ayala, H., Gladine, C., Wenk, M., Galano, J., Durand, T., Stark, K.D., Barbas, C., Garscha, U., Gelhaus, S.L., Ceglarek, U., Flamand, N., Griffin, J., Ahrends, R., Zeldin, D.C., Schopfer, F.J., Quehenberger, O., Julian, R., Nicolaou, A., Blair, I.A., Murphy, M., Hammock, B.D., Freeman, B., Liebisch, G., Serhan, C.N., Köfeler, H.C., Jakobsson, P., Steinhilber, D., Gelb, M.H., Holcapek, M., Andrew, R., Giera, M., Fitzgerald, G.A., Murphy, R.C., Dennis, E.A., Ekroos, K., Milne, G.L., Gijón, M., Vesper, H.W., Wheelock, C.E., O'Donnell, V.B. 2025. Technical requirements for LC-MS/MS oxylipin analysis. Science Signaling. 18(887). https://doi.org/10.1126/scisignal.adw1245.