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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Obesity and Metabolism Research » Research » Publications at this Location » Publication #423045
Research Project: Utilizing Precision Approaches to Refine Dietary Guidance of Americans to Reduce Chronic Disease

Location: Obesity and Metabolism Research

Title: Technical requirements for LC-MS/MS oxylipin analysis

Author
item SCHEBB, NILS - University Of Wuppertal
item KAMPSCHULTE, NADJA - University Of Wuppertal
item HAGN, GERHARD - Karolinska Institute
item PLITZKO, KATHRIN - University Of Wuppertal
item MECKELMANN, SVEN - University Of Duisburg-Essen
item GHOSH, SOUMITA - University Of Pennsylvania
item JOSHI, ROBIN - University Of Pennsylvania
item KULIGOWSKI, JULIA - Health Research Institute Hospital La Fe (IIS LA FE)
item VUCKOVIC, DAJANA - Concordia University
item BOTANA, MARINA - Victoria University Of Wellington
item SÁNCHEZ-ILLANA, ÁNGEL - Valencia University
item ZANDKARIMI, FERESHTEH - Columbia University - New York
item DAS, ADITI - Georgia Institute Of Technology
item YANG, JUN - University Of California, Davis
item SCHMIDT, LOUIS - University Of Greifswald
item CHECA, ANTONIO - Karolinska University Hospital
item ROCHE, HELEN - University College Dublin
item ARMANDO, AARON - University Of California, San Diego
item EDIN, MATTHEW - National Institutes Of Health (NIH)
item LIH, FRED - National Institutes Of Health (NIH)
item HENAO, JUAN - Bpgbio, Inc
item MIYAMOTO, SAYURI - Universidade De Sao Paulo
item GIUFFRIDA, FRANCESCA - Nestle
item MOUSSAIEFF, ARIEH - Hebrew University Of Jerusalem
item DOMINGUES, ROSÁRIO - University Of Aveiro (UA)
item ROTHE, MICHAEL - Lipidomix
item HINZ, CHRISTINE - Shimadzu Uk
item DAS, UJJALKUMAR - University Of Pennsylvania
item RUND, KATHARINA - University Of Wuppertal
item TAHA, AMEER - University Of California, Davis
item HOFSTETTER, ROBERT - University Of Jena
item WERNER, MARKUS - University Of Jena
item KAHNT, ASTRID - Goethe University
item BERTRAND-MICHEL, JUSTINE - University Of Toulouse
item LE FAOUDER, PAULINE - University Of Toulouse
item GURKE, ROBERT - Goethe University
item THOMAS, DOMINIQUE - Goethe University
item TORTA, FEDERICO - National University Of Singapore
item BIAGINI, DENISE - University Of Pisa
item IDBORG, HELENA - Karolinska Institute
item LOMONACO, TOMMASO - University Of Pisa
item LIU, JUN-YAN - Chongqing University
item FEDOROVA, MARIA - Technical University Dresden
item BARDEN, ANNE - The University Of Western Australia
item MORI, TREVOR - University Of Western Australia
item KENNEDY, PAUL - Leiden University Medical Center
item MAXEY, KIRK - Leiden University Medical Center
item IVANISEVIC, JULIJANA - University Of Lausanne
item AYALA, HECTOR GALLART - University Of Lausanne
item GLADINE, CÉCILE - Clermont Universite, Universite D'Auvergne, Unite De Nutrition Humaine
item WENK, MARKUS - Hamad Bin Khalifa University (HBKU)
item GALANO, JEAN-MARIE - University Of Montpellier
item DURAND, THIERRY - University Of Montpellier
item STARK, KEN - University Of Waterloo
item BARBAS, CORAL - Ceu San Pablo University
item GARSCHA, ULRIKE - University Of Greifswald
item GELHAUS, STACY - University Of Pittsburgh
item CEGLAREK, UTE - University Of Leipzig
item FLAMAND, NICOLAS - Laval University
item GRIFFIN, JULES - University Of Aberdeen
item AHRENDS, ROBERT - University Of Vienna
item ZELDIN, DARRYL - National Institutes Of Health (NIH)
item SCHOPFER, FRANCISCO - University Of Pittsburgh
item QUEHENBERGER, OSWALD - University Of California, San Diego
item JULIAN, RANDALL - Indigo Bioautomation, Inc
item NICOLAOU, ANNA - University Of Manchester
item BLAIR, IAN - University Of Pennsylvania
item MURPHY, MIKE - University Of Cambridge
item HAMMOCK, BRUCE - University Of California, Davis
item FREEMAN, BRUCE - University Of Pittsburgh
item LIEBISCH, GERHARD - University Of Regensburg
item SERHAN, CHARLES - Harvard Medical School
item KÖFELER, HARALD - Universitat Graz
item JAKOBSSON, PER-JOHAN - Karolinska Institute
item STEINHILBER, DIETER - Goethe University
item GELB, MICHAEL - University Of Washington
item HOLCAPEK, MICHAL - University Of Pardubice
item ANDREW, RUTH - University Of Vienna
item GIERA, MARTIN - Leiden University Medical Center
item FITZGERALD, GARRET - University Of Pennsylvania
item MURPHY, ROBERT - University Of Colorado
item DENNIS, EDWARD - University Of California, San Diego
item EKROOS, KIM - Consultant
item MILNE, GINGER - Vanderbilt University Medical Center
item GIJÓN, MIGUEL - Leiden University Medical Center
item VESPER, HUBERT - Centers For Disease Control And Prevention (CDC) - United States
item WHEELOCK, CRAIG - Karolinska University Hospital
item O'DONNELL, VALERIE - Cardiff University

Submitted to: Science Signaling
Publication Type: Other
Publication Acceptance Date: 4/25/2025
Publication Date: 5/20/2025
Citation: Schebb, N.H., Kampschulte, N., Hagn, G., Plitzko, K., Meckelmann, S.W., Ghosh, S., Joshi, R., Kuligowski, J., Vuckovic, D., Botana, M.T., Sánchez-Illana, Á., Zandkarimi, F., Das, A., Yang, J., Schmidt, L., Checa, A., Roche, H.M., Armando, A.M., Edin, M.L., Lih, F.B., Henao, J., Miyamoto, S., Giuffrida, F., Moussaieff, A., Domingues, R., Rothe, M., Hinz, C., Das, U.S., Rund, K.M., Taha, A., Hofstetter, R.K., Werner, M., Kahnt, A., Bertrand-Michel, J., Le Faouder, P., Gurke, R., Thomas, D., Torta, F., Biagini, D., Idborg, H., Lomonaco, T., Liu, J., Fedorova, M., Barden, A., Mori, T.A., Kennedy, P., Maxey, K., Ivanisevic, J., Ayala, H., Gladine, C., Wenk, M., Galano, J., Durand, T., Stark, K.D., Barbas, C., Garscha, U., Gelhaus, S.L., Ceglarek, U., Flamand, N., Griffin, J., Ahrends, R., Zeldin, D.C., Schopfer, F.J., Quehenberger, O., Julian, R., Nicolaou, A., Blair, I.A., Murphy, M., Hammock, B.D., Freeman, B., Liebisch, G., Serhan, C.N., Köfeler, H.C., Jakobsson, P., Steinhilber, D., Gelb, M.H., Holcapek, M., Andrew, R., Giera, M., Fitzgerald, G.A., Murphy, R.C., Dennis, E.A., Ekroos, K., Milne, G.L., Gijón, M., Vesper, H.W., Wheelock, C.E., O'Donnell, V.B. 2025. Technical requirements for LC-MS/MS oxylipin analysis. Science Signaling. 18(887). https://doi.org/10.1126/scisignal.adw1245.
DOI: https://doi.org/10.1126/scisignal.adw1245

Interpretive Summary:

Technical Abstract: Lipids that incorporate oxygen molecules into their structures have a wide array of important biological activities, and the determination of their concentrations in biological samples are an important area of biological research. To ensure the highest data quality and comparability of these measurements in the research community, a working group was established within the International Lipidomics Society (ILS). This group convened a two webinars attended by 87 individuals world wide, with feedback resulting in the current Focus article on best practices and reporting standards for oxylipin analyses. These recommendations are fully aligned with the ILS Minimal Reporting Checklist which should be used alongside this for data reporting.