Submitted to: Poultry Science Association Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 8/16/1998
Publication Date: N/A
Citation: N/A Interpretive Summary:
Technical Abstract: Colonization of the ceca and organ invasion by different isolates of Campylobacter jejuni was investigated in day-of-hatch Leghorn chicks. Chicks were orally administered 100 to 1,000,000 colony forming units (CFUs) of each C. jejuni isolate. Seven days later, C. jejuni was enumerated in the ceca of test birds by plating on Campy-Cephex agar. Organ invasion by Campylobacter in such test birds was determined by enrichment of Campylobacter in Bolton¿s broth followed by plating on Campy-Cephex agar. Results indicated that different isolates of C. jejuni vary both in their ability to invade organs as well as their capacity to colonize the gastrointestinal tract. Collectively these results indicate that different isolates of C. jejuni can colonize the ceca of birds when given as low a dose as 100-1,000 CFUs. However, organ invasion only occurs when relatively high doses (1,000,000 CFUs) of C. jejuni were administered. Overall these results demonstrate that day-of-hatch Leghorn chicks can be used for studies on factors that affect both cecal colonization and organ invasion by C. jejuni.