Nutritional regulation of myogenesis and muscle physiology

Authors: Cleveland, Beth; Overturf, Kenneth; BIGA, PEGGY - University Of Auburn

Submitted to: Nutrition and Physiology of Fish and Shellfish
Publication Type: Book / Chapter
Publication Acceptance Date: 1/1/2025
Publication Date: 4/2/2025
Citation: Cleveland, B.M., Overturf, K.E., Biga, P. 2025. Nutritional regulation of myogenesis and muscle physiology. In: Kumar, V. editor. Nutrition and Physiology of Fish and Shellfish. 1st edition. p.597-621. https://doi.org/10.1016/B978-0-323-90873-3.00009-9.
DOI: https://doi.org/10.1016/B978-0-323-90873-3.00009-9

Interpretive Summary:

Technical Abstract: In 2022, nearly half of the worldwide population receives 20% of their animal protein from fish, more than double the number of individuals reported in 2000. For almost all seafood species, the muscle represents the primary commodity of interest as a rich source of protein and energy for human consumption. Therefore, maximizing muscle growth and optimizing its nutritional profile will improve product quantity and quality, thus increasing production efficiency and saleable product. The accretion of skeletal muscle in vertebrates and invertebrates requires both activation of anabolic intracellular signaling mechanisms and the presence of essential nutrients for building cellular components. This chapter will review the nutritional composition of the edible muscle, describe the myogenic mechanisms responsible for muscle growth, and review physiological and nutritional signals that regulate muscle mass. Ultimately, the chapter will conclude with a perspective of how nutritional strategies may be developed and utilized to enhance muscle growth.