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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #407590

Research Project: Nutrient Metabolism and Musculoskeletal Health in Older Adults

Location: Jean Mayer Human Nutrition Research Center On Aging

Title: Measuring health-related quality of life in sarcopenia: summary of the SarQoL psychometric properties

item BEAUDART, CHARLOTTE - University Of Liege
item REGINSTER, JEAN-YVES - University Of Liege
item SMITH, JOTHEESWARAN - World Health Organization (WHO) - Switzerland
item BAUTMANS, IVAN - Vrije Universiteit Brussel
item BAUER, JERGEN - Heidelberg University
item BURLET, NANSA - University Of Liege
item CESARE, MATTEO - University Of Milan
item CHERUBINI, ANTONIO - Inrca - Irccs Istituto Nazionale Di Ricovero E Cura Per Anziani
item COOPER, CYRUS - University Of Southampton
item CRUZ-JENTOFT, ALFONSO - Instituto Ramon Y Cajal De Investigacion Sanitaria (IRYCIS)
item DAWSON-HUGHES, BESS - Jean Mayer Human Nutrition Research Center On Aging At Tufts University
item FIELDING, ROGER - Jean Mayer Human Nutrition Research Center On Aging At Tufts University
item HARVEY, NICHOLAS - University Of Southampton
item LANDI, FRANCESCO - Irccs Humanitas Research Hospital
item LASLOP, ANDREA - Austrian Medicines And Medical Devices Agency
item MAGGI, STEFANIA - National Research Council - Italy
item MONTERO-ERRASQUIN, BEATRIZ - Hospital Universitario Ramón Y Cajal (IRYCIS)
item PRIETO YERRO, MARIA CON - Spanish Agency Of Medicines And Medical Products
item ROLLAND, YVES - University Of Toulouse
item RIZZZOLI, RENE - Geneva University Hospital
item VISSER, MARJOLEIN - Vrijie University (VU)

Submitted to: Aging Clinical Experimental Research
Publication Type: Review Article
Publication Acceptance Date: 5/8/2023
Publication Date: 8/1/2023
Citation: Beaudart, C., Reginster, J., Smith, J., Bautmans, I., Bauer, J., Burlet, N., Cesare, M., Cherubini, A., Cooper, C., Cruz-Jentoft, A.J., Dawson-Hughes, B., Fielding, R.A., Harvey, N.C., Landi, F., Laslop, A., Maggi, S., Montero-Errasquin, B., Prieto Yerro, M., Rolland, Y., Rizzzoli, R., Visser, M. 2023. Measuring health-related quality of life in sarcopenia: summary of the SarQoL psychometric properties. Aging Clinical Experimental Research.

Interpretive Summary:

Technical Abstract: There is currently an increasing emphasis on patient-centered research. Indeed, patient perspectives are widely recognized as a key element in the evaluation of health interventions. Therefore, the provision of specific and validated Patient Reported Outcome Measures that emphasize the lived experience of patients suffering from specific diseases is very important. In the field of sarcopenia, the only validated specific health-related quality of life (HRQoL) instrument available is the Sarcopenia Quality of Life questionnaire (SarQoL). This self-administrated HRQoL questionnaire, developed in 2015, consists of 55 items arranged into 22 questions and has currently been translated into 35 languages. Nineteen validation studies performed on SarQoL have consensually confirmed the capacity of SarQoL to detect difference in HRQoL between older people with and without sarcopenia, its reliability and its validity. Two further observational studies have also indicated its responsiveness to change. A short form SarQoL, including only 14 items has further been developed and validated to reduce the potential burden of administration. This review aims to provide to researchers, clinicians, regulators, pharmaceutical industries and other stakeholders a clear summary of comprehensive evidence on the SarQoL questionnaire published up to January 2023.