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Research Project: Intervention Strategies to Control and Eradicate Foreign Animal Diseases of Swine

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Title: Editorial: Insights of important mammalian viruses: Infection, pathogenesis and drugs

item LI, YIHAN - Jiangxi Agricultural University
item Gladue, Douglas
item LI, SHA - Jiangxi Agricultural University
item DENG, LIN - Kobe University
item SHEN, CHAO - Wuhan University
item AGUILAR, PATRICIA - University Of Texas Medical Branch
item WANG, TING - Jiangxi Agricultural University
item KONG, LINGBAO - Jiangxi Agricultural University

Submitted to: Frontiers in Microbiology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 2/8/2023
Publication Date: 2/21/2023
Citation: Li, Y., Gladue, D.P., Li, S., Deng, L., Shen, C., Aguilar, P., Wang, T., Kong, L. 2023. Editorial: Insights of important mammalian viruses: Infection, pathogenesis and drugs. Frontiers in Microbiology.

Interpretive Summary: Editorial on the accepted articles in the research topic in Frontiers: Insights of important mammalian viruses: Infection, pathogenesis and drugs.

Technical Abstract: COVID-19, has brought new attention to the importance of new or emerging pathogenic viruses as a major threat to global health. Viruses have evolved multiple mechanisms to counteract host immunity that can be similar or drastically different for various viruses, making it difficult to control viruses using a single countermeasure. To further increase the complexity of controlling viruses, during replication viruses can vary genetically providing the viruses with the ability to overcome a countermeasure. As has been demonstrated by SARS-CoV-2, the viruses can evolve changing from the original target strains. Understanding the molecular mechanisms involved in how different viruses evade the immune system, or how different mutations could cause species shift is of great importance, especially for mammalian viruses. Evasion of immune system and/or genetic evolution can influence the virulence of the viral species, with the potential to cause pandemics. This collection of articles and reviews updates information on the research into the pathogenesis, diagnostic methods and vaccine development for a number of important mammalian viruses, which could be exploited to control the spread of existing viral diseases and prevent future potential virus epidemics.