|KUEHNEMANN, CHISAKA - Jean Mayer Human Nutrition Research Center On Aging At Tufts University|
|WILEY, CHRISTOPHER - Jean Mayer Human Nutrition Research Center On Aging At Tufts University|
Submitted to: Nature Metabolism
Publication Type: Review Article
Publication Acceptance Date: 2/7/2023
Publication Date: 3/2/2023
Citation: Kuehnemann, C., Wiley, C. 2023. Cholesterol drives inflammatory senescence. Nature Metabolism. https://doi.org/10.1038/s42255-023-00758-2.
Technical Abstract: Cell cycle arrest and secretions of senescent cells are both subject to metabolic control. In this issue of Nature Metabolism, Roh et. al. show that lysosomal partitioning of cholesterol potentiates inflammatory secretion during senescence.