Skip to main content
ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #403214
Research Project: Nutrient Metabolism and Musculoskeletal Health in Older Adults

Location: Jean Mayer Human Nutrition Research Center On Aging

Title: Cholesterol drives inflammatory senescence

Author
item KUEHNEMANN, CHISAKA - Jean Mayer Human Nutrition Research Center On Aging At Tufts University
item WILEY, CHRISTOPHER - Jean Mayer Human Nutrition Research Center On Aging At Tufts University

Submitted to: Nature Metabolism
Publication Type: Review Article
Publication Acceptance Date: 2/7/2023
Publication Date: 3/2/2023
Citation: Kuehnemann, C., Wiley, C. 2023. Cholesterol drives inflammatory senescence. Nature Metabolism. https://doi.org/10.1038/s42255-023-00758-2.
DOI: https://doi.org/10.1038/s42255-023-00758-2

Interpretive Summary:

Technical Abstract: Cell cycle arrest and secretions of senescent cells are both subject to metabolic control. In this issue of Nature Metabolism, Roh et. al. show that lysosomal partitioning of cholesterol potentiates inflammatory secretion during senescence.