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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #372142

Research Project: Nutrient Metabolism and Musculoskeletal Health in Older Adults

Location: Jean Mayer Human Nutrition Research Center On Aging

Title: Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures

item KANIS, JOHN - University Of Sheffield
item HARVEY, NICK - University Of Southampton
item MCCLOSKEY, EUGENE - University Of Sheffield
item BRUYERE, OLIVIER - University Of Liege
item VERONESE, NICOLA - Cnr Neuroscience Institute
item LORENTZON, MATTIAS - Australian Catholic University
item COOPER, CYRUS - University Of Southampton
item RIZZOLI, RENE - University Hospitals Of Geneva
item ADIB, GEMMA - Syrian National Osteoporosis Society
item AL-DAGHRI, NASSER - King Saud University
item CAMPUSANO, C - Universidad De Los Andes
item CHANDRAN, MANJU - Singapore General Hospital
item DAWSON-HUGHES, BESS - Jean Mayer Human Nutrition Research Center On Aging At Tufts University
item JAVAID, KASSIM - University Of Oxford
item JIWA, FAMIDA - Osteoporosis Canada
item JOHANSSON, HELENA - Australian Catholic University
item LEE, J - Beacon Hospital
item LIU, ENWU - Australian Catholic University
item MESSINA, OSVALDO - Consultant
item MKINSI, OUAFA - Ibn Rochd University Hospital
item PINTO, DANIEL - Marquette University
item PRIETO-ALHAMBRA, DANIEL - University Of Oxford
item SAAG, K - University Of Alabama
item XIA, WEIBO - Peking Union Medical College Hospital
item ZAKRAOUI, LEITH - University Of Tunis El Manar
item REGINSTER, JEAN-YVES - University Of Liege

Submitted to: Osteoporosis International
Publication Type: Review Article
Publication Acceptance Date: 9/18/2019
Publication Date: 11/13/2019
Citation: Kanis, J.A., Harvey, N.C., Mccloskey, E., Bruyere, O., Veronese, N., Lorentzon, M., Cooper, C., Rizzoli, R., Adib, G., Al-Daghri, N., Campusano, C., Chandran, M., Dawson-Hughes, B., Javaid, K., Jiwa, F., Johansson, H., Lee, J.K., Liu, E., Messina, O.D., Mkinsi, O., Pinto, D., Prieto-Alhambra, D., Saag, K., Xia, W., Zakraoui, L., Reginster, J. 2019. Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International.

Interpretive Summary:

Technical Abstract: Summary: Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction: The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods: Clinical perspective and updated literature search. Results: The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions: A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.