Location: Virus and Prion ResearchTitle: PhyloVirus: Inferring virus reassortment and recombination, and a visualization tool for phylogenetic networks
|MUBARAKI, F - Iowa State University|
|MARKIN, A - Iowa State University|
|MILLER, L - Iowa State University|
|EULENSTEIN, O - Iowa State University|
Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 9/9/2019
Publication Date: 11/4/2019
Citation: Mubaraki, F., Anderson, T.K., Markin, A., Miller, L., Eulenstein, O. 2019. PhyloVirus: Inferring virus reassortment and recombination, and a visualization tool for phylogenetic networks [abstract].The 100th Annual Conference of Research Workers in Animal Diseases.Abstract No. 182.
Technical Abstract: RNA virus diversity is the result of mutation, recombination, and reassortment. Traditional virus evolution studies rely on single-gene phylogenetic trees that do not account for all these processes. Phylogenetic network algorithms can do so but are hampered by computational limitations. We introduce an efficient software package with a graphical user interface called PhyloVirus that constructs and allows visualization of phylogenetic trees, median trees, and networks. We apply our software to swine influenza A virus (IAV), quantifying reassortment events in the evolution of H3N2 viruses and identify novel reassorted viruses.