Location: Virus and Prion ResearchTitle: Respiratory immunology – a flu focus
|WYMORE-BRAND, MEGHAN - Oak Ridge Institute For Science And Education (ORISE)
Submitted to: American Association of Swine Veterinarians Annual Meeting
Publication Type: Proceedings
Publication Acceptance Date: 11/19/2018
Publication Date: 3/9/2019
Citation: Vincent, A.L., Wymore-Brand, M. 2019. Respiratory immunology – a flu focus. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 9-12, Orlando, Florida. Not available.
Technical Abstract: Because of its plasticity and complicated epidemiology in swine, IAV presents a challenge to the respiratory immune system and, thus, a challenge to control through vaccination. A greater understanding has occurred in recent years with regard to the intricate immune responses to exposure, both primary and repeated exposures in a lifetime, as well as responses to vaccines administered to immune and partially immune individuals. However, many of these types of studies are lacking in the swine host. Improved knowledge of protective responses at the respiratory mucosa and how different vaccine platforms and viral antigens alter these responses are needed in swine to improve our ability to control this important pathogen that affects so many species.