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Title: Obesity and eating disorders in integrative prevention programmes for adolescents: Protocol for a systematic review and meta-analysis

item BARCO LEME, ANA - Children'S Nutrition Research Center (CNRC)
item Thompson, Deborah - Debbe
item LENZ DUNKER, KARIN - Federal University - Brazil
item NICKLAS, THERESA - Children'S Nutrition Research Center (CNRC)
item PHILIPPI, SONIA - Universidade De Sao Paulo
item LOPEZ, TABBETHA - University Of Houston
item VEZINA-IM, LYDI - Children'S Nutrition Research Center (CNRC)
item BARANOWSKI, TOM - Children'S Nutrition Research Center (CNRC)

Submitted to: BMJ Open
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/20/2018
Publication Date: 4/19/2018
Citation: Barco Leme, A.C., Thompson, D.J., Lenz Dunker, K.L., Nicklas, T., Philippi, S.T., Lopez, T., Vezina-Im, L.A., Baranowski, T. 2018. Obesity and eating disorders in integrative prevention programmes for adolescents: Protocol for a systematic review and meta-analysis. BMJ Open. 8(4):e020381. doi:10.1136/bmjopen-2017-020381.

Interpretive Summary: Preventing obesity among adolescents may be easier if principles of obesity and eating disorder prevention are combined, since they share a number of risk factors. This study will compare interventions that targeted obesity prevention alone with those that combined obesity and eating disorder prevention on measures of body composition. This study will also assess the extent to which the combined interventions changed disordered eating behaviors. The results will inform us as to whether combined interventions offer greater promise for obesity prevention.

Technical Abstract: Obesity and eating disorders are public health problems that have lifelong financial and personal costs and common risk factors, for example, body dissatisfaction, weight teasing and disordered eating. Obesity prevention interventions might lead to the development of an eating disorder since focusing on weight may contribute to excessive concern with diet and weight. Therefore, the proposed research will assess whether integrating obesity and eating disorder prevention procedures ('integrated approach') do better than single approach interventions in preventing obesity among adolescents, and if integrated approaches influence weight-related outcomes. Integrated obesity and eating disorder prevention interventions will be identified. Randomised controlled trials and quasi-experimental trials reporting data on adolescents ranging from 10 to 19 years of age from both sexes will be included. Outcomes of interest include body composition, unhealthy weight control behaviours and body satisfaction measurements. MEDLINE/PubMed, PsycINFO, Web of Science and SciELO will be searched. Data will be extracted independently by two reviewers using a standardised data extraction form. Trial quality will be assessed using the Cochrane Collaboration criteria. The effects of integrated versus single approach intervention studies will be compared using systematic review procedures. If an adequate number of studies report data on integrated interventions among similar populations (k>5), a meta-analysis with random effects will be conducted. Sensitivity analyses and meta-regression will be performed only if between-study heterogeneity is high (I2 =75%). Ethics approval will not be required as this is a systematic review of published studies. The findings will be disseminated through conference presentations and peer-reviewed journals.