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ARS Home » Southeast Area » Mississippi State, Mississippi » Crop Science Research Laboratory » Corn Host Plant Resistance Research » Research » Publications at this Location » Publication #352711
Title: Survey of candidate genes for maize resistance to infection by Aspergillus flavus and/or aflatoxin contamination

Author
item Hawkins, Leigh
item Warburton, Marilyn
item TANG, JULIET - Us Forest Service (FS)
item TOMASHEK, JOHN - Integrated Laboratories Systems
item ALVES, DAFNE - Mississippi State University
item OGUNOLA, OLUWASEUN - Mississippi State University
item Smith, Jesse
item Williams, William

Submitted to: Toxins
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/24/2018
Publication Date: 1/31/2018
Citation: Hawkins, L.K., Warburton, M.L., Tang, J., Tomashek, J., Alves, D., Ogunola, O.F., Smith, J.S., Williams, W.P. 2018. Survey of candidate genes for maize resistance to infection by Aspergillus flavus and/or aflatoxin contamination. Toxins. 10(2):61.

Interpretive Summary: Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using different genetic tools. However, only a small percentage of these candidates have been validated under field conditions, and their relative contribution to resistance, if any, is unknown. This study presents a consolidated list of candidate genes identified in past studies or in-house studies, with descriptive data including genetic location, gene annotation, known protein identifiers, published expression data, and associated pathway information, if known. A candidate gene pipeline to test the phenotypic effect of any maize DNA sequence on aflatoxin accumulation resistance was used in this study to determine any measurable effect on polymorphisms within or linked to the candidate gene sequences, and the results are published here.

Technical Abstract: Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies. However, only a small percentage of these candidates have been validated under field conditions, and their relative contribution to resistance, if any, is unknown. This study presents a consolidated list of candidate genes identified in past studies or in-house studies, with descriptive data including genetic location, gene annotation, known protein identifiers, published expression data, and associated pathway information, if known. A candidate gene pipeline to test the phenotypic effect of any maize DNA sequence on aflatoxin accumulation resistance was used in this study to determine any measurable effect on polymorphisms within or linked to the candidate gene sequences, and the results are published here.