Location: Cool and Cold Water Aquaculture ResearchTitle: Draft Genome Sequence of the Fish Pathogen Flavobacterium columnare Strain MS-FC-4 Author
|Bartelme, Ryan - University Of Wisconsin|
|Barbier, Paul - University Of Wisconsin|
|Lapatra, Scott - Retired Non ARS Employee|
|Mcbride, Mark - University Of Wisconsin|
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 4/17/2018
Publication Date: 5/17/2018
Citation: Bartelme, R.P., Barbier, P., Lipscomb, R.S., LaPatra, S.E., Evenhuis, J., McBride, M.J. 2018. Draft Genome Sequence of the Fish Pathogen Flavobacterium columnare Strain MS-FC-4. Genome Announcements. 6(20):e00429-18. https://doi.org/10.1128/genomeA.00429-18.
DOI: https://doi.org/10.1128/genomeA.00429-18 Interpretive Summary: Columnaris disease in rainbow trout is caused by the pathogen Flavobacterium columnare. We report the sequencing and draft assembly of the Flavobacterium columnare strain MS-FC-4 genome sequence. This strain was isolated from a diseased rainbow trout and is currently being used as a reference strain to study host- pathogen interaction. The availability of the genome sequence will help identify virulence factors and potential targets for vaccine development, with the ultimate goal of reducing loss from columnaris disease and the need for antibiotic application.
Technical Abstract: Flavobacterium columnare MS-FC-4 is a highly virulent genetic group 1 (formerly genomovar I) strain isolated from rainbow trout (Oncorhynchus mykiss). The draft genome consists of three contigs totaling 3,449,277 base pairs with 2,811 predicted open reading frames. F. columnare MS-FC-4 is a model strain for functional genomic analyses.