Author
LUO, M - University Of California | |
Gu, Yong | |
DANIELA, P - Johns Hopkins University School Of Medicine | |
HAO, W - University Of Georgia | |
DEAL, K - University Of California | |
HUO, N - University Of California | |
ZHU, T - Dominican University Of California | |
WANG, L - University Of California | |
WANG, Y - University Of California | |
MC GUIRE, P - University Of California | |
LIU, S - University Of California | |
LONG, H - University Of California | |
RAMASAMY, R - University Of California | |
RODRIGUEZ, J - University Of California | |
SONNY, V - University Of California | |
YUAN, L - University Of California | |
WANG, Z - Chinese Agricultural University | |
XIA, Z - University Of California | |
XIAO, L - University Of California | |
Anderson, Olin | |
OUYANG, S - Chinese Agricultural University | |
LIANG, Y - Chinese Agricultural University | |
ZIMIN, A - Johns Hopkins University School Of Medicine | |
PERTEA, G - Johns Hopkins University School Of Medicine | |
DAI, X - University Of California | |
DAWSON, M - University Of California | |
MULLER, H-G - University Of California | |
TWARDZIOK, S.O. - Helmholtz Centre For Environmental Research | |
KUGLER, K - Helmholtz Centre For Environmental Research | |
SPANNAGL, M - Helmholtz Centre For Environmental Research | |
MAYER, K.F.X. - Helmholtz Centre For Environmental Research | |
LEROY, P - Institut National De La Recherche Agronomique (INRA) | |
LI, P - Agriculture And Agri-Food Canada | |
YOU, FRANK - Agriculture And Agri-Food Canada | |
SUN, Q - Chinese Agricultural University | |
LI, Z - Chinese Agricultural University | |
LYONS, E - University Of Arizona | |
WICKER, T - University Of Zurich | |
SALZBERG, S - Johns Hopkins University School Of Medicine | |
DEVOS, K.M. - University Of Georgia | |
DVORAK, J - University Of California | |
BENNETZEN, J - University Of Georgia |
Submitted to: Nature
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 10/9/2017 Publication Date: 11/15/2017 Citation: Luo, M., Gu, Y.Q., Daniela, P., Hao, W., Deal, K., Huo, N., Zhu, T., Wang, L., Wang, Y., Mcguire, P., Liu, S., Long, H., Ramasamy, R., Rodriguez, J., Sonny, V., Yuan, L., Wang, Z., Xia, Z., Xiao, L., Anderson, O.D., Ouyang, S., Liang, Y., Zimin, A., Pertea, G., Dai, X., Dawson, M., Muller, H., Twardziok, S., Kugler, K., Spannagl, M., Mayer, K., Leroy, P., Li, P., You, F., Sun, Q., Li, Z., Lyons, E., Wicker, T., Salzberg, S., Devos, K., Dvorak, J., Bennetzen, J. 2017. Genome sequence of the progenitor of the wheat D genome Aegilops tauschii. Nature. 551:498-502. doi:10.1038/nature24486. DOI: https://doi.org/10.1038/nature24486 Interpretive Summary: The global food supply depends on three foundation cereals: rice, maize, and wheat. In 2014, wheat was grown on 222 million ha, exceeding rice and maize by 21 and 36%, respectively, making it the most widely grown cereal. Genetic evidence indicates that hexaploid bread wheat originated from hybridization of tetraploid wheat T. turgidum with diploid Tausch’s goatgrass Aeligops tauschii. Among the contributions of the Ae. tauschii genome to hexaploid wheat are tolerance to abiotic stress, bread-making properties, and broad adaptability. Ae. tauschii has also been a rich breeding resource for resistance to wheat diseases, including the aggressive stem rust race UG99. In this work, a reference-quality DNA sequence for the Ae. tauschii genome was produced and assembled using a combination of three independent methods. Comparisons of Ae. tauschii constructed chromosomes with genomic sequences of rice, sorghum, foxtail millet, and Brachypodium distachyon revealed that the large Ae. tauschii genome has been evolving more quickly than the small genomes of these species. We also show that the distribution patterns of genes, transposable elements, organellar DNA insertions, and simple sequence repeats evolved in response to the patterns of recombination rates along the Ae. tauschii chromosomes. The genomic resource generated in this work is freely available to the wheat community for many aspects of crop improvement research, including cloning of agronomically important traits and marker assisted breeding. Technical Abstract: Aegilops tauschii is the diploid progenitor of the D genome of hexaploid wheat and an important genetic resource for wheat. A reference-quality sequence for the Ae. tauschii genome was produced with a combination of ordered-clone sequencing, whole-genome shotgun sequencing, and BioNano optical genome mapping. Synergy among BioNano optical maps for different Ae. tauschii genotypes and the wheat D genome was exploited in super-scaffolding and pseudomolecule construction. Comparisons of Ae. tauschii pseudomolecules with genomic sequences of rice, sorghum, foxtail millet, and Brachypodium distachyon revealed that the large Ae. tauschii genome has been evolving more quickly than the small genomes of those species. The analysis of Ae. tauschii pseudomolecules showed that the distribution patterns of genes, transposable elements, organellar DNA insertions, and simple sequence repeats and the rate of gene collinearity decay evolved in response to the patterns of recombination rates along the Ae. tauschii chromosomes. |